1. a. Department of Hepatobiliary Surgery丨 b. National Local Joint Engineering Research Center for Precision Surgery &
Regenerative Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an Shaanxi 710061, China丨 2. a. Qide College丨
b. Zong lian College, Xi’an Jiaotong University, Xi’an Shaanxi 710061, China
Abstract：Objective To explore the feasibility of magnetic hydrogel based on magnetic anchor technique for endoscopic submucosal
dissection of gastric. Methods Using 4 fresh isolated pig stomachs as models, sodium alginate ferric oxide solution and calcium
agent were injected under the hypothesized lesion mucosa. After gelation, the external anchor magnet was placed, the magnet
hydrogel was attracted by the anchor magnet, and the lesion mucosa was lifted to assist the endoscopic submucosal lesion removal.
Results Endoscopic submucosal dissection was successfully performed in 4 isolated pig stomachs. Sodium alginate ferric oxide
solution was injected smoothly and gelation reaction occurred rapidly after meeting with calcium agent. Under the magnetic
attraction of the anchor magnet, the diseased mucosa was sucked up and pulled, and the mucosal dissection surface was fully exposed
and maintained a certain tension, which greatly improved the operation experience of the operator and facilitated the endoscopic
submucosal dissection. Conclusion Submucosal injection of magnetic hydrogel is feasible in endoscopic gastric mucosal dissection.
张苗苗1a,1b，刘培楠1b,2a，张涵芷1b,2a，徐庶钦1b,2b，牟星宜1b,2b，雷凤萍1b,2a，史爱华1b，马锋1b，吕毅1a,1b，严小鹏1a,1b. 磁性水凝胶用于内镜胃黏膜下剥离术的实验研究[J]. 中国医疗设备, 2021, 36(5): 25-27.
ZHANG Miaomiao1a,1b，LIU Peinan1b,2a，ZHANG Hanzhi1b,2a，XU Shuqin1b,2b，MOU Xingyi1b,2b，LEI Fengping1b,2a，SHI Aihua1b，MA Feng1b，LV Yi1a,1b，YAN Xiaopeng1a,1b. Experimental Study of Magnetic Hydrogel for Endoscopic Submucosal Dissection of Gastric. China Medical Devices, 2021, 36(5): 25-27.
