Objective The purpose of this study is to optimize the operation arrangement and improve the utilization rate of operating room and patient satisfaction through the intelligent operation scheduling system. Methods Based on the data center, the system was developed by SQL Server 2016, Visual Studio 2019 and C#, and realized the automatic scheduling of B/S website in the mode of Vue+.Net Core. Results By leveraging a data mid-platform, this system has achieved the intellectualization and automation of surgical scheduling and personnel rostering. It has also incorporated an intelligent reminder function for scheduling results. Furthermore, it has established a Business Intelligence (BI) system specifically for operating rooms, significantly enhancing the efficiency, convenience, and safety of surgical services within hospitals.After the application of the system, the preoperative waiting time was reduced by 16%, the overtime time of nurses was reduced by 16%, the efficiency of operation scheduling was increased by 62%, the frequency of operation adjustment was reduced by 35%, the error rate of operation was reduced by 60%, the average daily operation volume was increased by 8.2%, the patient satisfaction was increased by 1.3%, and the operation accuracy rate was increased by 22.5%. The differences in each index were statistically significant (P<0.05). Conclusions The intelligent surgical scheduling system is a pivotal tool in modern hospital management. It optimizes surgical scheduling through intelligent and automated processes, thereby improving operating room utilization, minimizing surgical delays, and enhancing both patient satisfaction and medical quality.