Study on Accumulated Dose of Cervical Cancer Internal and External Radiation by Deformation Registration and Direct Superposition Method

LIU Zicheng1, CUI Xiangli2, LIU Lingling2, WANG Jinyun2, FEI Zhenle1,3

China Medical Devices ›› 2022, Vol. 37 ›› Issue (4) : 14-18.

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China Medical Devices ›› 2022, Vol. 37 ›› Issue (4) : 14-18. DOI: 10.3969/j.issn.1674-1633.2022.04.004
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Study on Accumulated Dose of Cervical Cancer Internal and External Radiation by Deformation Registration and Direct Superposition Method

  • LIU Zicheng1, CUI Xiangli2, LIU Lingling2, WANG Jinyun2, FEI Zhenle1,3
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Abstract

Objective To analyze the difference of the cumulative dose of different dose superposition methods in cervical cancer internal and external radiation, and evaluate the accuracy of direct superposition method. Methods The radiotherapy plan of 10 patients with cervical cancer who received internal and external irradiation was retrospectively analyzed. With the deformation registration method in the MIM software, the fractional internal radiation dose and external radiation dose of each patient were superimposed and compared with the direct superposition method. Results When superimposing the fractional internal radiation radiotherapy dose, it was found that the average values of the tumor target area D90%, bladder D2cc, and rectum D2cc obtained by the direct superposition method were 6.54, 1.66, 4.05 Gy higher than the results of the deformation registration method, and there were statistical differences (P<0.05). When the internal and external radiation doses were superimposed, it was found that the average values of the tumor target area D90%, the bladder D2cc, and the rectum D2cc obtained by the direct superposition method were 5.35, 0.78, and 6.72 Gy higher than the results of the deformation registration method, and tumor target area D90% and rectum D2cc were statistical differences (P<0.05), bladder D2cc was not statistical differences (P>0.05). Conclusion The normal tissue dose assessed by direct superposition method is too high, it may be appropriate to relax the actual work conditions.

Key words

radiotherapy plan / deformation registration method / direct superposition / radiation dose / cervical carcinoma

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LIU Zicheng, CUI Xiangli, LIU Lingling, et al. Study on Accumulated Dose of Cervical Cancer Internal and External Radiation by Deformation Registration and Direct Superposition Method[J]. China Medical Devices, 2022, 37(4): 14-18 https://doi.org/10.3969/j.issn.1674-1633.2022.04.004

References

[1] 刘宗超,李哲轩,张阳,等.2020全球癌症统计报告解读[J].肿瘤 综合治疗电子杂志,2021,7(2):1-14.
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