Dosimetric Difference Between AXB Algorithm and AAA Algorithm in VMAT Radiotherapy for Cervical Cancer

ZHANG Xiangxue, ZHANG Qian, SUN Chuntang, YIN Rutie, LI Qingli, CHEN Yazheng

China Medical Devices ›› 2022, Vol. 37 ›› Issue (2) : 39-42.

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China Medical Devices ›› 2022, Vol. 37 ›› Issue (2) : 39-42. DOI: 10.3969/j.issn.1674-1633.2022.02.009
RESEARCH WORK

Dosimetric Difference Between AXB Algorithm and AAA Algorithm in VMAT Radiotherapy for Cervical Cancer

  • ZHANG Xiangxue, ZHANG Qian, SUN Chuntang, YIN Rutie, LI Qingli, CHEN Yazheng
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Abstract

Objective To analyze and compare the photon dose algorithm (AcurosXB) and the anisotropic analysis algorithm (Anisotropic Analytical Algorithm, AAA) in Volumetric Intensity-Modulated Arc Therapy (VMAT) after cervical cancer surgery. The dosimetric difference. Methods A total of 24 postoperative patients with cervical cancer were selected to design the VMAT plan using AXB algorithm and AAA algorithm on the Eclipse 15.5 treatment planning system, and generate corresponding EPID verification plans. The dosimetric parameters of target area and organs at risk were compared. Results The D2%, D5%, D98% and Dmax of the target area calculated by the two algorithms showed significant statistical differences (P<0.05). The maximum dose of AAA algorithm was (48.1±17.2) Gy, and the maximum dose of AXB algorithm was (48.7±28.7) Gy, and the PTV conformity index has significant statistical differences (P=0.047). There were significant differences in Dmean between the bones of the organs at risk (ilium and sacrum), left femoral head and right femoral head (P<0.05). And except Dmin, D95%, D98% and V25 of the small intestine, the results of all other reference indexes AAA algorithm were lower than the AXB algorithm. There was no statistical difference in the verification plans between the two algorithms (P>0.05). Conclusion Although there are certain dosimetric differences between AXB algorithm and AAA algorithm in cervical cancer VMAT, they both meet the dosimetry and clinical requirements, and there is no statistically significant difference in the verification pass rate. Both algorithms can be applied to clinical treatment.

Key words

AXB algorithm / AAA algorithm / cervical cancer radiotherapy / intensity-modulated radiotherapy / dose verification

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ZHANG Xiangxue, ZHANG Qian, SUN Chuntang, et al. Dosimetric Difference Between AXB Algorithm and AAA Algorithm in VMAT Radiotherapy for Cervical Cancer[J]. China Medical Devices, 2022, 37(2): 39-42 https://doi.org/10.3969/j.issn.1674-1633.2022.02.009

References

[1] Rana S.Clinical dosimetric impact of Acuros XB and analytical anisotropic algorithm (AAA) on real lung cancer treatment plans: review[J].Int J Canc Ther Oncol,2014,2(1):2-13.
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