1. a. Department of Hepatobiliary Surgery丨 b. National Local Joint Engineering Research Center for Precision Surgery &
Regenerative Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an Shaanxi 710061, China丨 2. Qide College,
Xi’an Jiaotong University, Xi’an Shaanxi 710061, China
Abstract：Objective To investigate the feasibility of magnetic anastomosis ring designed based on magnetic shielding theory
for the preparation of gastric bypass surgery model in rats. Methods According to the theory of magnetic shielding, a magnetic
anastomosis ring with a shell of permalloy and a core of NdFeB for gastrointestinal anastomosis reconstruction in rats was designed
and manufactured. Twelve sprague-dawley (SD) rats were used as animal models. After laparotomy, the jejunum was dissected at 16
cm from the distal end of the Treitz ligament. According to the operation mode of gastric bypass, the magnetic anastomosis ring with
magnetic shielding structure was used to complete gastrointestinal anastomosis and intestinal anastomosis in turn. After operation, the
position of the magnet was observed according to the direct and lateral side X-ray photograph, and the discharge time of the magnet
was recorded. The survival situation of the animals was observed. Results Among the 12 SD rats, except for one died unexpectedly
due to anesthesia, the other 11 rats successfully completed the gastrointestinal bypass surgery by magnetic anastomosis, and the
operation time was (49.73±6.34) min. The animals survived well after operation. All magnets were discharged smoothly through
the digestive tract, and the excretion time was (9.14±1.89) d. Conclusion The magnetic anastomosis ring with shell-core structure
based on magnetic shielding theory can effectively avoid the unplanned phase absorption between multiple magnets in a narrow
space, and can be used in animal model preparation of gastric bypass surgery in rats with the advantages of simple operation and high
success rate.
张苗苗1a,1b，李恒1b,2，吝怡1b,2，魏欣怡1b,2，李美豫1b,2，刘俊杰1b,2，吕毅1a,1b，严小鹏1a,1b. 基于磁屏蔽设计的磁吻合环建立大鼠胃旁路手术的实验研究[J]. 中国医疗设备, 2021, 36(5): 19-21.
ZHANG Miaomiao1a,1b，LI Heng1b,2，LIN Yi1b,2，WEI Xinyi1b,2，LI Meiyu1b,2，LIU Junjie1b,2，LV Yi1a,1b，YAN Xiaopeng1a,1b. Experimental Study on Gastric bypass Surgery in Rats by Magnetic Anastomosis
Based on Magnetic Shielding Design. China Medical Devices, 2021, 36(5): 19-21.
