Abstract：Objective In this study, different algorithms were used for dose calculation and verification of SRT plans in typical cases
of liver cancer. The accuracy and reliability of SRT plans under different conditions were analyzed and evaluated, so as to provide
certain reference for the selection of different algorithms in clinical application. Methods In this study, 33 liver cancer patients
treated with CK in our department were chosen. The dose calculation and verification were done to evaluate using Ray-Tracing
(RT) and Monte Carlo (MC) algorithms respectively. In addition, 10 typical cases were selected to do the dose verificaiton with
solid water. The differences between the two algorithms and its selection of application were analyzed and discussed. Results The
average dose value of RT algorithm in the target area of left lobe liver cancer was 58.21 Gy, and the average value of MC algorithm
was 57.76. The difference between two algorithms was 0.45 Gy (0.78%). The mean value of RT algorithm in right lobe liver cancer
was 55.82 Gy, and the average value of MC algorithm was 54.60 Gy, with a difference of 1.22 Gy (2.23%). After re-calculation
using MC algorithm, the average dose of esophagus, stomach, spinal cord, intestinal tract, duodenum and liver were all decreased,
with statistical significance (P<0.05). Taking the dose calculation of MC algorithm as the baseline, RT algorithm was overestimated
by 1.09% in patients with liver cancer, and the difference was statistically significant (P<0.05). Uniform solid water was used for
verification, the difference between the calculated value of point dose and the measured value of RT and MC was within ±3%, and
the passing rate of γ analysis using 3%/2 mm standard was greater than 93%. Conclusion In this study, the systematic research
and measurement were carried out on dose calculation and verification of the RT and MC algorithms in liver tumor sites, and their
accuracy and deviation were verified, thus providing the basis for the selection and treatment implementation of SRT plans in liver
sites of CK system,which has a certain guiding significance for clinical practice.
葛瑞刚，解传滨，戴相昆，杨涛，王越，王树鑫，曲宝林，徐寿平. CyberKnife系统中肝癌计划实施剂量计算及验证的评价研究[J]. 中国医疗设备, 2021, 36(4): 132-136.
GE Ruigang, XIE Chuanbin, DAI Xiangkun, YANG Tao, WANG Yue, WANG Shuxin, QU Baolin, XU Shouping. Evaluation of Dose Calculation and Verfication Plan of Liver Cancer in CyberKnife. China Medical Devices, 2021, 36(4): 132-136.
