Research on Building Computer Model to Explore the Mechanical Mechanism of
Atlantoaxial Dislocation Caused by Basilar Invagination
LANG Dawei, BO Xuefeng
School of Biomedical Engineering, Capital Medical University (Beijing Key Laboratory of Fundamental Research on Biomechanics
in Clinical Application), Beijing 100069, China
Abstract：Objective To build a computer model, measure and analyze the correlation of morphological parameters among the degree
of basilar invagination, atlantoaxial dislocation, lateral joint deformity and odontoaxial deformity, so as to provide morphological
basis for studying the biomechanical mechanism of atlantoaxial dislocation caused by odontoid process and lateral joint deformity.
Methods Cervical CT scan data of 60 volunteers were collected and divided into normal control group, patients with basilar
depression without atlantoaxial dislocation group, and patients with basilar depression combined with atlantoaxial dislocation group,
20 cases in each group. Mimics Research 20.0 software was used to establish three-dimensional models. A series of morphological
parameters were measured and analyzed using IBM SPSS 21 software. Results There were statistically significant differences in
the distance from the tip of dentate process to the Chamberlain line, ADI, height of dentate process, height of dentate process/base
width, inclination Angle of dentate process 1 and 2, sagittal joint inclination Angle and craniocervical inclination Angle (P<0.05).
The height/base width of dentate process was negatively correlated with sagittal joint inclination angle (r=-0.687, P<0.001), while
the height and base width of dentate process were negatively correlated with basilar depression and atlantoaxial dislocation (r=0.691,
P<0.001). Sagittal joint obliquity was significantly positively correlated with basilar depression and atlantoaxial dislocation, while
craniocervical obliquity was only significantly positively correlated with basilar depression (r=0.644, P<0.001). Conclusion Deformities of
odontoid and lateral joint are the main causes of atlantoaxial dislocation in patients with basilar depression.
郎大卫，薄雪峰. 建立计算机模型探索颅底凹陷导致寰枢椎脱位的力学机制的研究[J]. 中国医疗设备, 2021, 36(3): 44-48.
LANG Dawei, BO Xuefeng. Research on Building Computer Model to Explore the Mechanical Mechanism of
Atlantoaxial Dislocation Caused by Basilar Invagination. China Medical Devices, 2021, 36(3): 44-48.
