Material Optimization Design of New Degradable Biliary Stent
ZHANG Lianga, MA Yalia, SHAO Wenb
a. Bidding and Supply Office; b. State Assets Management Office, The First Affiliated Hospital of Xi’an Jiaotong University,
Xi’an Shaanxi 710061, China
Abstract：In order to increase the degradable degree of biliary stent and improve the situation of easy displacement and biliary
restenosis of current biliary stent, a novel degradable biliary stent was designed with TAXOL-P3/4HB-PCL, and the structural
parameter were established. A total of 5 diameters of biliary stent were designed according to the size of bile duct for adults
and children of different ages. The effect of P3/4HB-PCL on the proliferation of fibroblasts was valued by MTT method. The
degradability of P3/4HB-PCL was analyzed by immersing it in PBS buffer. The results showed that P3/4HB-PCL had slight reactivity
with fibroblasts, good biocompatibility and good degradability
张亮a，马亚丽a，邵雯b. 新型可降解胆道支架的材料优化设计[J]. 中国医疗设备, 2020, 35(3): 52-55.
ZHANG Lianga, MA Yalia, SHAO Wenb. Material Optimization Design of New Degradable Biliary Stent. China Medical Devices, 2020, 35(3): 52-55.
