Fundamental Study on Evaluation of Frontal Lobe Epilepsy Based on Characteristics
of Resting-State Brain Functional Network
CAO Xinzhi1, QIAN Zhiyu1, ZHANG Zhiqiang2, XU Qiang2, TANG Liming2
1. College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing Jiangsu 211106, China;
2. Department of Medical Imaging, Jinling Hospital, Nanjing Jiangsu 210002, China
Abstract：Objective The purpose of this paper was to analyze the characteristics of brain functional network under the influence of
frontal lobe epilepsy by resting-state functional magnetic resonance imaging, and to find out the possible evaluation index of brain
damage in frontal lobe epilepsy. Methods Typical parameters in graph theory analysis were obtained, including edges, node degree,
node efficiency and betweenness centrality. Two-sample t test was carried out for the results in patients with frontal lobe epilepsy
and normal controls. The changes of brain functional network under the influence of frontal lobe epilepsy were analyzed to provide
evidence for evaluating frontal lobe epilepsy. The correlation analysis of the characteristics with seizure duration and frequency was
further conducted. Results Compared with the control group, the frontal lobe epilepsy patients had significant statistical results in
the parameters of edge, nodal degree, nodal efficiency and betweenness centrality. Moreover, we found that there were correlations
between the results and the frequency and duration of epilepsy. Conclusion The characteristics of resting-state brain functional
network based on graph theory analysis may be used as an evaluation index of frontal lobe epilepsy and provide a basis for the
evaluation of frontal lobe epilepsy.
曹新志1，钱志余1，张志强2，许强2，汤黎明2. 基于静息态脑功能网络特征的额叶癫痫评价基础研究[J]. 中国医疗设备, 2020, 35(3): 47-51.
CAO Xinzhi1, QIAN Zhiyu1, ZHANG Zhiqiang2, XU Qiang2, TANG Liming2. Fundamental Study on Evaluation of Frontal Lobe Epilepsy Based on Characteristics
of Resting-State Brain Functional Network. China Medical Devices, 2020, 35(3): 47-51.
