Abstract：The retina is a biological tissue with high oxygen metabolism. When there is an ocular lesion or systemic disease of the
human body, there are abnormal retinal blood oxygen metabolism and regulating disorders correspondingly. The measurement
of retinal oxygen saturation level is of clinical significance. Currently, scientific-grade detectors are generally employed in both
commercially developed instruments and laboratory prototypes that allow for the non-invasive detection of retinal oxygen saturation.
However, these scientific-grade detectors are very expensive and to some extent it hinders the mass production and sales of the
retinal oxygen saturation measurement instruments. In this study, a non-invasive retinal blood oxygen saturation measurement system
was designed based on a fundus camera with the single-lens reflex (SLR) camera as the detector. Specifically, the Nikon D70 SLR
camera was used as the detector in the system for its ideal spectral response curves of the green and red channels. By extracting the
corresponding retinal imaging information on the green and red channels, the functional blood oxygen saturation could be further
calculated through a lab developed software. The method proposed in this study offers a new idea for the economic version of
the retinal oxygen saturation measurement system. The system is able to measure the oxygen saturation with good accuracy and
repeatability, and it has the potential for further study and clinic applications associated with ophthalmic and systemic diseases.
邹达，冯夕萌，刘刚军，任秋实，卢闫晔. 基于单镜头反光式相机的视网膜血氧饱和度无创测量系统[J]. 中国医疗设备, 2020, 35(3): 28-32.
ZOU Da, FENG Ximeng, LIU Gangjun, REN Qiushi, LU Yanye. A Non-Invasive Retinal Blood Oxygen Saturation Measurement System
Based on the Single-Lens Reflex Camera. China Medical Devices, 2020, 35(3): 28-32.
