Abstract：Objective To analyze the value of CT texture and morphological features in the diagnosis of pulmonary pure ground glass
nodules (pGGN). Methods The data and CT images of 102 pGGN patients who were operated in our hospital from January 2015 to
June 2018 were analyzed retrospectively. According to the classification standard of lung adenocarcinoma, the patients were divided
into three groups: non infiltrated group (n=40), micro infiltrated group (n=32) and infiltrated group (n=30). The CT morphological
and texture signs of the three groups were analyzed to diagnose the invasiveness of pGGN in the lungs. Results The working
characteristic curve of subjects was drawn. The diagnostic sensitivity was 67.32% and the specificity was 83.65% when the boundary
value of lesion size was 8.6; the area under the curve was 0.786, the diagnostic sensitivity was 84.09% and the specificity was
78.51% when the boundary value of CT was -514 HU. The CT manifestations of AAH, AIS, MIA and I-ADC in pggn patients were
mostly the same or overlapped. Logistic univariate analysis of all the manifestations showed that the shape and edge of the lesions
were divided into leaf sign, internal air gap sign, peripheral structural vascular changes and pleural depression were the risk factors
of pggn infiltration (P<0.05). Logistic regression analysis showed that the edge shape was lobular sign, vascular changes around the
lesion and pleural depression were independent risk factors for pggn infiltration. The comprehensive judgment of CT texture features
and signs to identify whether pGGN was infiltrating showed that CT diagnostic sensitivity was 83.87%, specificity was 92.50%, and
accuracy was 87.25%. Conclusion It has a high diagnostic value for the invasion of pggn through the comprehensive judgment of
CT texture features and morphological signs, which is worthy of research and promotion.
冯光，贺延法，董建立. CT纹理特征和形态征象对肺部纯磨玻璃结节侵袭性的诊断价值[J]. 中国医疗设备, 2020, 35(7): 77-80.
FENG Guang, HE Yanfa, DONG Jianli. Diagnostic Value of CT Texture Features and Morphologic Features in the Invasiveness of
Pulmonary Pure Ground Glass Nodules. China Medical Devices, 2020, 35(7): 77-80.
