Simulation Study on Efficacy Evaluation of Neoadjuvant Chemotherapy for
Breast Cancer Based on Electrical Impedance Scanning Imaging
WANG Ruiqing1,2, MA Hang1, LI Haoting1, SHI Xuetao1, LIU Benyuan1, JI Zhenyu1
1. School of Military Biomedical Engineering, Air Force Military Medical University of PLA, Xi’an Shaanxi 710032, China;
2. Department of Medical Engineering, 82 Group Military Hospital of PLA, Baoding Hebei 071000, China
Abstract：Objective To study the ability of the electrical impedance scanning (EIS) system detecting the changes of breast cancer
tissues during the neoadjuvant chemotherapy for breast cancer. Methods A fine breast electrical impedance simulation model was
constructed to evaluate the ability of the system detecting changes in size and conductivity of the cancerous tissues during the
neoadjuvant chemotherapy. The fitting curves and regression equations were acquired by analyzing simulating data, and the indicators
were eventually obtained from the regression equations. Results The ability of the system detecting changes had a linear relationship
with both the size and the conductivity of the cancerous tissues. When the system’s detecting threshold value was 0.05, the smallest
detectable change of long-diameter of the cancerous tissue was 2.17 mm, and the least detectable conductivity’s change was 0.78 S/m.
Conclusion The EIS system enables sensitive detection of changes in size and conductivity of cancerous tissues, and the simulation
results can provide theoretical guidance for EIS application in the evaluation of neoadjuvant chemotherapy for breast cancer.
王瑞青1,2，马航1，李昊庭1，史学涛1，刘本源1，季振宇1. 基于电阻抗扫描成像的乳腺癌新辅助化疗疗效评价的仿真研究[J]. 中国医疗设备, 2020, 35(2): 31-35.
WANG Ruiqing1,2, MA Hang1, LI Haoting1, SHI Xuetao1, LIU Benyuan1, JI Zhenyu1. Simulation Study on Efficacy Evaluation of Neoadjuvant Chemotherapy for
Breast Cancer Based on Electrical Impedance Scanning Imaging. China Medical Devices, 2020, 35(2): 31-35.
