Application of Transcranial Color-Code Sonography in Diagnosis of
Acute Toluene and Xylene Poisoning
YU Shanshan1, LI Bojian2, DING Hong1, LI Jinzhu1, LI Dandan 1
1. Department of Ultrasound, The Second Hospital of Heilongjiang Province, Harbin Heilongjiang 150000, China;
2. Department of Infectious Diseases, Harbin Infectious Diseases Hospital, Harbin Heilongjiang 150000, China
Abstract：Objective To investigate the clinical value of transcranial color-code sonography (TCCS) in the diagnosis of acute toluene
and xylene poisoning. Methods A total of 55 patients with acute toluene and xylene poisoning admitted to our hospital from May
2013 to May 2018 were selected as observation group, including 34 patients with mild poisoning and 21 patients with moderate
poisoning. Another 50 healthy adults were selected as control group. All subjects underwent TCCS examination. The observation
group underwent CT and MRI examinations after admission. The results of TCCS examination in observation group and control
group were compared, and the diagnostic results of CT and MRI in observation group were analyzed. Results There were significant
differences in MCA blood flow parameters between the intoxicated patients and the control group at admission (P<0.05). The blood
flow parameters Vp, Vd and Vm of MCA in moderate poisoning patients were significantly higher than those in mild poisoning
patients, and the levels of PI and RI were significantly lower than those in mild poisoning patients (P<0.05). After treatment, MCA
blood flow parameters of mild and moderate poisoning patients were significantly improved compared with those at admission, and
there was no significant difference compared with the control group (P>0.05). The results of imaging examination at admission
showed that the positive rate of TCCS in mild and moderate poisoning patients was significantly higher than that of abnormal CT and
MRI (P<0.05). Conclusion Through the assessment of MCA blood flow parameters, TCCS can detect the changes of hemodynamics
in acute toluene and xylene poisoning, and provide reliable evidence for early and accurate diagnosis. It is more sensitive than spiral
CT and MRI, and has clinical diagnostic value.
于珊珊1，李伯健2，丁红1，李金珠1，李丹丹1. 经颅彩色多普勒超声在急性甲苯、二甲苯中毒诊断中的应用研究[J]. 中国医疗设备, 2019, 34(12): 61-63.
YU Shanshan1, LI Bojian2, DING Hong1, LI Jinzhu1, LI Dandan 1. Application of Transcranial Color-Code Sonography in Diagnosis of
Acute Toluene and Xylene Poisoning. China Medical Devices, 2019, 34(12): 61-63.
