Abstract:Objective To study the dosimetric characteristics of non-coplanar volumetric modulation arc therapy (ncVMAT) for
postoperative cervical cancer. Methods Ten patients with postoperative cervical cancer were selected in our department from May
2017 to August 2017. Coplanar plan and non-coplanar plan were designed for each patient respectively. Then, the dose distribution
of target volume and normal tissues between coplanar plan and non-coplanar plan was compared using a paired t test. Results There
was no statistically significant difference in the dose distribution between two plans in bladder, rectum and small intestines. The V10,
V20, V30, and V40 of ncVMAT in the ilium and bilateral femoral head were lower than that in coplanar plan (P<0.05). Conclusion
In cervical cancer radiotherapy, ncVMAT can reduce the dose and volume of the pelvic hematopoietic system, and decrease the
hematologic toxicity caused by radiotherapy.