川北医学院附属医院 a. 肿瘤科（医学影像四川省重点实验室，四川省肿瘤学重点学科）；b. 核医学科，四川 南充 637000
Short-Term Clinical Effect and Side Effects of Cervical Cancer Patients Treated by
VMAT Combined with Three Dimensional Intracavitary Brachytherapy
CAO Lua, LI Xianfua, ZHOU Yeqina, MA Xiaojiea, GUI Yana, XIE Lia, GUO Feia, LI Supingb, TAN Bangxiana
a. Department of Oncology, Key Laboratory of Medical Imaging in Sichuan Province, Key Subject of Oncology in Sichuan Province;
b. Department of Nuclear Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong Sichuan 637000, China
Abstract：Objective To retrospectively investigate the short-term clinical effect and side effects of cervical cancer patients treated
by VMAT combined with three dimensional intracavitary brachytherapy. Methods Forty cervical cancer patients received radical
radiotherapy in our department from April to October in 2017 were selected. Firstly all cases were undergone external VMAT
irradiation (D95%), which was performed at 55 Gy/25 times, then another 192Ir three-dimensional cavity treatment was performed
for 4 to 5 times. Short-term curative effect and side effects were observed. Results All 40 patients were followed up for 6 months.
The efficacy evelution result showed that there were 20 cases of complete remission (50%), 16 cases of partial remission (40%), 3
cases of stable disease (7.5%), and 1 case of progress disease (2.5%), with a total efficiency of 90%. The main side events included
bone marrow depression (30 cases, 75%), gastrointestinal reaction (11 cases, 27.5%), and urinary system reaction (20 cases, 50%).
Conclusion VMAT combined with three dimensional intracavitary brachyterapy can achieve good short-term effect for cervical cancer
patients, and the relevant side effects will not affect the successful completion of radiotherapy after timely symptomatic treatment.
However, the long-term effect, side effects and the corresponding influence factors still need further follow-up observation and study.
曹璐a，李贤富a，周业琴a，马晓洁a，皈燕a，谢力a，郭飞a，李素平b，谭榜宪a. 宫颈癌VMAT外照射联合三维腔内后装治疗的近期疗效和不良反应分析[J]. 中国医疗设备, 2018, 33(12): 97-99.
CAO Lua, LI Xianfua, ZHOU Yeqina, MA Xiaojiea, GUI Yana, XIE Lia, GUO Feia, LI Supingb, TAN Bangxiana. Short-Term Clinical Effect and Side Effects of Cervical Cancer Patients Treated by
VMAT Combined with Three Dimensional Intracavitary Brachytherapy. China Medical Devices, 2018, 33(12): 97-99.
