Abstract：Objective To evaluate the feasibility of quantitative method for second-generation dual-source dual-energy CT (DECT)
iodine maps in assessing changes in hepatic perfusion in patients with liver cirrhosis. Methods According to the Child-Pugh
grading for liver functionality, 30 volunteers with normal liver functionality as well as 30 patients with liver cirrhosis were enrolled
in this study, respectively. The hepatic arterial phase (Ia), intravenous iodine value (Ip) (AIF=Ia/Ip) and the difference of iodine
concentration in portal vein (PVIC= IP-Ia) were measured and compared between the two groups. Results There was no significant
difference in Ia, Ip, AIF and PVIC between liver cirrhosis group and normal group as well as right lobe (P>0.05). Statistical
significant difference of parameters in odine maps were found between the two groups (P<0.05). There was no significant difference
in CT values between the group with normal liver functionality and the group with liver cirrhotic in arterial phase (P>0.05), but
significant difference was found in CT values in venous phase between the two groups (P<0.05). Conclusion The second-generation
DECT iodine images can reflect the changes of liver perfusion in patients with liver cirrhosis and further provide a new method for
quantitative assessment of patients with liver cirrhosis.
唐永强，石磊，李剑，石明国. 双能量CT碘图评估肝硬化血流灌注的可行性分析[J]. 中国医疗设备, 2017, 32(11): 15-17.
TANG Yongqiang, SHI Lei, LI Jian, SHI Mingguo. Feasibility Analysis of Dual Energy CT Iodine Maps in Assessing Blood Perfusion of Cirrhosis. China Medical Devices, 2017, 32(11): 15-17.
