Comparative Analysis of Dynamic Magnetic Resonance Imaging Quantitative
Parameters and Pathological Results in the Diagnosis of Benign and
Malignant Breast Lesions
HU Hai-fenga, WANG Yingb,LIU Yinga, BAI Lian-jieb,DENG Jia-jiab,ZHANG Chun-yua
a.Department of Nuclear Magnetic
Resonance; b.Department of Ultrasound,
Second Affiliated Hospital of Qiqihar
Medical University, Qiqihar
Heilongjiang 61000, China
Abstract：Objective This paper aimed to investigate the application of the quantitative parameters of
dynamic enhanced MRI (DCE-MRI), microvessel density (MVD) and microvessel density (VEGF) in
the diagnosis of benign and malignant breast lesions. Methods A total of 128 patients who underwent
DCE-MRI scans from March 2015 to July 2016 were enrolled in this study. The difference of quantitative
parameters between benign group and malignant group was analyzed. The ROC curve was used to
analyze the difference between benign and malignant group. Results There were significant statistical
differences between the benign group and the malignant group. The specificity of Ktrans and Kep was 88.6%
and 95.1%, respectively; the sensitivity of Ktrans and Kep was 87.9% and 68.7%, respectively. There was a
strong correlation with MVD (r=0.597; 0.612) in the Ktrans and Kep values of breast cancer patients, there
was a strong correlation between Ktrans and Kep (r=0.781; 0.763). Conclusion There is a strong correlation
between the quantitative parameters of DCE-MRI and the pathological findings of MVD or VEGF, and it
has a good effect in the diagnosis of benign and malignant breast lesions.
胡海峰a，王影b，刘莹a，白连杰b，邓佳佳b，张春宇a. 动态磁共振成像定量参数同病理结果在诊断良恶性乳腺病变中的对比分析[J]. 中国医疗设备, 2017, 32(7): 64-67.
HU Hai-fenga, WANG Yingb,LIU Yinga, BAI Lian-jieb,DENG Jia-jiab,ZHANG Chun-yua. Comparative Analysis of Dynamic Magnetic Resonance Imaging Quantitative
Parameters and Pathological Results in the Diagnosis of Benign and
Malignant Breast Lesions. China Medical Devices, 2017, 32(7): 64-67.
