Abstract:Objective To evaluate papillary muscle function in coronary artery disease patients by twodimensional
speckles tracking imaging (2D-STI), this paper investigated the correlation of the papillary
muscle function and the degree of coronary artery stenosis, and provided the basis for screening the
parameters of evaluating papillary muscle function. Methods Collecting 96 patients with coronary
heart disease as case group and 66 healthy volunteers as control group, two-dimensional images and the
three-dimensional full volume dynamic images of left ventricular were collected. Routine parameters
for evaluation of papillary muscle function: fractional shortening (FS), length between the posterior or
anterior papillary muscle tip sand the contralateral anterior mitral annular (APM-AMA, PPM-AMA),
mitral leaflet closure (MLC), interdistance papillary muscle (IPMD), AngⅠ (the angle between the
anterior papillary muscle and the anterior LV free wall), AngⅡ (the angle between the posterior papillary
muscle and the anterior LV free wall), anterior and posterior papillary muscle longitudinal strain (ALS,
PLS), peak time (PT) and delay time (DT) were aquiredred respectively. Papillary muscle function among
the groups were compared, and the relationship between papillary muscle function and the degree of
coronary artery stenosis was explored. Results Compared with control group, there were no significant
statistically differences in routine parameters of left ventricular internal diameter at end-diastole (LVIDd),
left ventricular end-diastolic volume (LVEDV) and left ventricular systolic diastolic volume (LVSDV)
(P>0.05). PPM-FS, IPMD, MLC, ALS, PLS and DT in case group were significantly different compared with control group (P<0.05). ALS, PLS, MLC, APM-FS, PPM-FS, IPMD were significantly correlated
with Gensini score (r=-0.60, -0.78, 0.53, -0.43, -0.53, 0.54, P<0.05). Conclusion Application of 2D-STI
technology can accurate quantitative evaluation of coronary artery disease myocardial ischemia caused
by papillary muscle dysfunction, and measurement parameters of ALS and PLS measured by 2D-STI
were most significantly corrected with the degree of coronary artery stenosis.
孟湘a,刘昕a,张金库b. 超声心动图评价冠心病患者乳头肌功能的临床研究[J]. 中国医疗设备, 2017, 32(4): 54-57.
MENG Xianga, LIU Xina, ZHANG Jin-kub. Clinical Research of Echocardiography in Assessment of Papillary Muscle
Function in Patients with Coronary Artery Disease. China Medical Devices, 2017, 32(4): 54-57.