Abstract：Objective To measure the change of Intermedin (IMD) and N-Terminal pro-Brain
Natriuretic Peptide (NT-proBNP) so as to explore their clinical significance in diagnosis of the
elderly patients with chronic heart failure (CHF). Methods According to the American New York
Heart Association (NYHA) standard, the elderly CHF patients were divided into Cardiac Function
Grade I Group, Grade II Group, Grade III Group and Grade IV Group for comparative analysis. The
level of serum IMD and NT-proBNP in elderly CHF patients and the normal Control Group were
measured. Results IMD of Grade IV Group was lower than that of Grade I, II Group and III Group
with statistically significant difference (P<0.05). IMD of Grade III Group was lower than that of
Grade I and II Group with statistically significant difference (P<0.05). The level of NT-proBNP in
CHF patients was significantly higher than the normal Control Group (P<0.01), and was increased
following the increase of grade (P<0.05). The plasma levels of IMD and NT-proBNP were negatively
correlated (r=-0.573, P<0. 001). Conclusion The changes of IMD and NT-proBNP contribute to the
understanding of the severity and prognosis assessment of elderly patients with chronic heart failure.
Patients’ lower IMD indicates lower prognosis assessment.
何凯. IMD、脑钠肽的水平在老年慢性心力衰竭中的临床意义[J]. 中国医疗设备, 2016, 31(6): 56-59.
HE Kai. Clinical Significance of Application of Serum NT-proBNP and IMD in
Diagnosis of Elderly Patients with Chronic Heart Failure. China Medical Devices, 2016, 31(6): 56-59.
