Abstract：As the leading cause of death in the world, the diagnosis and treatment of vascular diseases
has received more and more attention. The minimally invasive endovascular procedures which require
effective intraoperative guidance, such as 2D X ray fluoroscopy, become the preferred option for patients
because the patient trauma, risk of complications and recovery times can be reduced. The 2D-fluoroscopyguided
endovascular navigation, however, is limited by a number of factors: insufficient analysis of
the preoperative images; lacking of 3D real-time images of instruments and surrounding anatomy and
exposure to repeated doses of X-ray radiation. To solve these problems, an intraoperative fluoroscopyfree
endovascular navigation method is introduced in this paper from three aspects: the preoperative
prior information based on image analysis, the fusion of preoperative and intraoperative images and the
intuitive navigation images. The proposed intraoperative fluoroscopy-free navigation method can provide
3D quantitative and intuitive navigation information for doctors to assist endovascular interventional
therapy.
