Abstract：Objective To explore the feasibility of using exercise-stress dual-energy mode CT (DE-CT) to
assess coronary artery flow. Methods Data of 18 patients with suspected coronary arteries disease who
had undergone cardiac DE-CT were retrospectively analyzed. The patients were divided into two groups:
10 patients who performed exercise-stress CT as the experimental group and 8 patients who performed
rest CT as the control. We reconstructed an iodine map and composite images at 120 kV using raw data
with scan parameters of 100 and 140 kV. We measured mean attenuation in the coronary artery proximal
to the distal portion on both the iodine map and 120 kV images. Coronary enhancement ratio (CER) was
calculated and was used to estimate the coronary enhancement. The difference between the two groups
were compared. Results Coronary stenosis was identified as a reduction in 50% of diameter on CT
angiogram. Myocardial ischemia was diagnosed by adenosine-stress myocardial perfusion scintigraphy.
The iodine map showed that CER was significantly lower in ischemic territories (0.76±0.05) and stenosed
coronary arteries (0.77±0.05) than in nonischemic territories (0.99±0.31, P<0.05) and nonstenosed
coronary arteries (1.05±0.35, P<0.05). The 120 kV images showed no difference in CER between these
two groups. Conclusion CER on the iodine map is a candidate method for evaluate coronary artery
stenosis and myocardial ischemia.
李剑a，石磊b，王栋a，刘从伟a，王帅a，姜文龙a，刘豹a，郑敏文a，石明国a. 运动负荷心脏双能量CT成像评估冠状
动脉血流量的初步分析研究[J]. 中国医疗设备, 2016, 31(3): 50-52.
LI Jiana, SHI Leib, WANG Donga,LIU Cong-weia, WANG Shuaia,JIANG Wen-longa, LIU Baoa,ZHENG Min-wena,SHI Ming-guoa. Functional Assessment of Coronary Artery Flow Using Exercise-stress
Dual-energy CT: A Preliminary Analytical Research. China Medical Devices, 2016, 31(3): 50-52.
