Effectiveness of Application of Combination Plain CT Scan and Clinical Features in Diagnosis of Multi-Organ Impairment with Tuberous Sclerosis Complex
ZHANG Yue1, HU Ying2, ZHANG Wei1
1. Department of Radiology, Wuhan No.1
Hospital, Wuhan Hubei 430022, China;
2. Department of Radiology, Tongji
Hospital, Tongji Medical College,
Huazhong University of Science and
Technology, Wuhan Hubei 430030, China
Abstract：Objective To make an exploration of the plain CT scanning features and clinical features of multi-organ impairment with tuberous sclerosis complex (TSC) to investigate the combination of both features in diagnosis of TSC. Methods The plain CT scan imaging findings and the clinical features of the 11 TSC patients who had been diagnosed pathologically or clinically were reviewed. Results Of 11 patients with TSC, one typical triad (epilepsy, mental retardation and facial sebaceous adenoma) was found and the remaining ten cases had only 1 or 2 symptoms separately. All the eleven patients underwent head or chest orabdominal multi-slice spiral plain CT scan. As a result, sub-ependymal nodules were detected in every case, sub-ependymal giant cell astrocytoma was detected in 1 case, and non-calcified pulmonary nodules were revealed in 4 cases. Eight patients had renal angiomyolipomas, while four had liver angiomyolipomas. Bone involvement was discovered in 5 cases. Conclusion The combination of plain CT scan imaging findings and clinical features of TSC offered sufficient basis for the diagnosis of multi-organ impairment of TSC, especially for the epilepsy patient from whom the sub-ependymal nodules were revealed by using plain CT scan as a useful indication of the diagnosis of TSC.
张跃，胡颖，张蔚. 多排螺旋CT平扫结合临床表现在多系统损害结节性硬化症诊断中的应用价值[J]. 中国医疗设备, 2015, 30(12): 57-59.
ZHANG Yue, HU Ying, ZHANG Wei. Effectiveness of Application of Combination Plain CT Scan and Clinical Features in Diagnosis of Multi-Organ Impairment with Tuberous Sclerosis Complex. China Medical Devices, 2015, 30(12): 57-59.
