Application of Nanosecond Pulsed Electric Field in Cutaneous Malignant Tumors
MAO Yuntao1, Essette Turgan2, CHEN Yonggang3, BAO Qi4
1. Operation Room, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou Zhejiang 310003, China;
2. Division of Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi Xinjiang 830054, China; 3. Zhejiang
Provincial Key Laboratory of Pulsed Power Translational Medicine, Hangzhou Zhejiang 311100, China; 4. Department of Plastic and
Reconstructive Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou Zhejiang 310003, China
Abstract：Cutaneous malignant tumors include basal cell carcinoma, squamous cell carcinoma, and malignant melanoma. The
treatment of cutaneous malignant tumors mainly includes radical surgery and systemic therapy. However, the damage to surrounding
healthy tissue caused by surgery and the side effects of systemic treatment affect the prognosis of patients to a certain extent.
Nanosecond pulsed electric field (nsPEF) is a new electrical pulse ablation technology with the advantages of being minimally
invasive, non-thermal energy, non-drug, and almost no scar. Previous studies have demonstrated that nsPEF can effectively induce
tumor cell apoptosis and trigger a strong immune response. However, little is known about the theory of nsPEF in China. This paper
aims to summarize the application of nsPEF in cutaneous malignant tumors at home and abroad and to provide a reference for the
clinical application of nsPEF.
毛云涛1，艾赛提·吐尔干2，陈永刚3，包祺4. 纳秒脉冲电场技术的皮肤恶性肿瘤应用前景[J]. 中国医疗设备, 2023, 38(5): 65-69.
MAO Yuntao1, Essette Turgan2, CHEN Yonggang3, BAO Qi4. Application of Nanosecond Pulsed Electric Field in Cutaneous Malignant Tumors. China Medical Devices, 2023, 38(5): 65-69.
