基于磁压榨技术的膀胱造瘘动物实验研究

张苗苗1a,1b,冒健骐2a,任宇翔2a,任炳屹2a,盖敬慈2b,张涵芷2b, 蓝婷2b,王伊睿2b,刘培楠2b,史爱华1b,吕毅1a,1b,严小鹏1a,1b

中国医疗设备 ›› 2022, Vol. 37 ›› Issue (6) : 12-14.

PDF(1938 KB)
PDF(1938 KB)
中国医疗设备 ›› 2022, Vol. 37 ›› Issue (6) : 12-14. DOI: 10.3969/j.issn.1674-1633.2022.06.004
专论

基于磁压榨技术的膀胱造瘘动物实验研究

  • 张苗苗1a,1b,冒健骐2a,任宇翔2a,任炳屹2a,盖敬慈2b,张涵芷2b, 蓝婷2b,王伊睿2b,刘培楠2b,史爱华1b,吕毅1a,1b,严小鹏1a,1b
作者信息 +

Experimental Study on Cystostomy Based on Magnetic Compression Technique in Animals

  • ZHANG Miaomiao1a,1b, MAO Jianqi2a, REN Yuxiang2a, REN Bingyi2a, GAI Jingci2b, ZHANG Hanzhi2b, LAN Ting2b, WANG Yirui2b, LIU Peinan2b, SHI Aihua1a,1b, LV Yi1a,1b, YAN Xiaopeng1a,1b
Author information +
文章历史 +

摘要

目的 探讨磁压榨技术(Magnetic Compression Technique,MCT)用于膀胱造瘘的可行性。方法 根据MCT原理,结 合新西兰兔下尿道解剖特点,设计用于膀胱造瘘的子磁体(Daughter Magent,DM)和母磁体(Parent Magnet,PM)。 以6只新西兰兔为动物模型,静脉麻醉后经尿道置入DM至膀胱内,在耻骨联合上方腹壁外放置PM。DM和PM可自动相 吸。密切观察实验兔术后一般状况,记录磁体脱落时间。磁体脱落后安乐死处死实验兔获取膀胱造瘘口标本,肉眼观察膀 胱造瘘口形成情况。结果 6只实验兔均成功实施了MCT膀胱造瘘,术中DM在导丝引导下顺利置入膀胱内,DM和PM自动 对位吸合良好。术后10~13 d DM和PM脱落,膀胱造瘘口建立,开腹探查见膀胱与腹壁粘连愈合良好,盆腔无明显粘连。 肉眼观察膀胱造瘘口标本可见膀胱与腹壁粘连愈合紧密,造瘘口通畅性良好。结论 基于MCT的膀胱造瘘具有操作简便、创 伤小、造瘘口形成良好等优点,该技术有望用于临床。

Abstract

Objective To investigate the feasibility of magnetic compression technique (MCT) for cystostomy. Methods The daughter magnet (PM) and parent magnets (PM) for cystostomy were designed according to the principle of MCT and the anatomical characteristics of the lower urethra of New Zealand rabbits. Six New Zealand rabbits were used as animal models. After intravenous anesthesia, the DM was inserted into the bladder through the urethra, and the PM was placed outside the abdominal wall above the symphysis pubis. The DM and PM can be automatically attracted. The general conditions of rabbits after operation were closely observed and the expulsion time of magnets was recorded. The rabbit was euthanized after the magnet fell off to obtain the fistula specimen and observe the formation of cystostomy by naked eye. Results Cystostomy by MCT was successfully performed in 6 rabbits. The DM was successfully inserted into the bladder under the guidance of the guide wire. Then the DM and PM were automatically aligned and attracted well. Ten to thirteen days after surgery, the DM and PM fell off and the cystostomy was established. Laparotomy showed that the adhesion between bladder and abdominal wall was well healed, and no obvious adhesion was found in pelvic cavity. The specimen of fistula was observed by naked eye, which showed that the bladder and abdominal wall adhered and healed closely and the fistula had good patency. Conclusion Cystostomy based on MCT has the advantages of simple operation, small trauma and good fistula formation, which is expected to be used in clinic.

关键词

磁外科 / 磁吻合 / 磁压榨技术 / 膀胱造瘘 / 动物实验

Key words

magnetic surgery / magnamosis / magnetic compression technique / bladder colostomy / animal experiments

引用本文

导出引用
张苗苗1a,1b,冒健骐2a,任宇翔2a,任炳屹2a,盖敬慈2b,张涵芷2b, 蓝婷2b,王伊睿2b,刘培楠2b,史爱华1b,吕毅1a,1b,严小鹏1a,1b. 基于磁压榨技术的膀胱造瘘动物实验研究[J]. 中国医疗设备, 2022, 37(6): 12-14 https://doi.org/10.3969/j.issn.1674-1633.2022.06.004
ZHANG Miaomiao1a,1b, MAO Jianqi2a, REN Yuxiang2a, REN Bingyi2a, GAI Jingci2b, ZHANG Hanzhi2b, LAN Ting2b, WANG Yirui2b, LIU Peinan2b, SHI Aihua1a,1b, LV Yi1a,1b, YAN Xiaopeng1a,1b. Experimental Study on Cystostomy Based on Magnetic Compression Technique in Animals[J]. China Medical Devices, 2022, 37(6): 12-14 https://doi.org/10.3969/j.issn.1674-1633.2022.06.004
中图分类号: R608   

参考文献

[1] 李双平,王振兴,李承勇,等.一次性腹腔穿刺引流管在膀胱穿刺 造瘘术中的应用研究[J].中国药物与临床,2018,18(5):789-790.

基金

陕西省重点研发计划一般项目(2021SF-163);陕西省 创新能力支撑计划(2020KJXX-022);西安交通大学大学生创新训 练项目

PDF(1938 KB)

402

Accesses

0

Citation

Detail

段落导航
相关文章

/