Abstract：Objective To analyze and compare the photon dose algorithm (AcurosXB) and the anisotropic analysis algorithm
(Anisotropic Analytical Algorithm, AAA) in Volumetric Intensity-Modulated Arc Therapy (VMAT) after cervical cancer surgery.
The dosimetric difference. Methods A total of 24 postoperative patients with cervical cancer were selected to design the VMAT
plan using AXB algorithm and AAA algorithm on the Eclipse 15.5 treatment planning system, and generate corresponding EPID
verification plans. The dosimetric parameters of target area and organs at risk were compared. Results The D2%, D5%, D98% and Dmax
of the target area calculated by the two algorithms showed significant statistical differences (P<0.05). The maximum dose of AAA
algorithm was (48.1±17.2) Gy, and the maximum dose of AXB algorithm was (48.7±28.7) Gy, and the PTV conformity index
has significant statistical differences (P=0.047). There were significant differences in Dmean between the bones of the organs at risk
(ilium and sacrum), left femoral head and right femoral head (P<0.05). And except Dmin, D95%, D98% and V25 of the small intestine,
the results of all other reference indexes AAA algorithm were lower than the AXB algorithm. There was no statistical difference in
the verification plans between the two algorithms (P>0.05). Conclusion Although there are certain dosimetric differences between
AXB algorithm and AAA algorithm in cervical cancer VMAT, they both meet the dosimetry and clinical requirements, and there is no
statistically significant difference in the verification pass rate. Both algorithms can be applied to clinical treatment.
张向学，张谦，孙春堂，尹如铁，李清丽，陈亚正. AXB算法与AAA算法在宫颈癌VMAT放射治疗中的剂量学差异[J]. 中国医疗设备, 2022, 37(2): 39-42.
ZHANG Xiangxue, ZHANG Qian, SUN Chuntang, YIN Rutie, LI Qingli, CHEN Yazheng. Dosimetric Difference Between AXB Algorithm and AAA Algorithm in
VMAT Radiotherapy for Cervical Cancer. China Medical Devices, 2022, 37(2): 39-42.
