Research of 3D Printing Individualized Compensation in Radiotherapy of Anal Canal Cancer
ZENG Biao1, DOU Yujiao2, TAN Jianfeng1, LUO Longjun1, HUANG Shixiong1, ZHOU Qionghui1, ZENG Degao1,
XU Shilei1, ZHU Wanlin1, ZHANG Jiutang1
1. Department of Radiological Physics and Technology, Hunan Cancer Hospital/The Affilicated Cancer Hospital of Xiangya School
of Medicine, Central South University, Changsha Hunan 410013, China; 2. Outpatient Service Office, Xiangya Hospital Central
South University, Changsha Hunan 410008, China
Abstract：Objective To provide a 3D printing method for personalized customized tissue compensation for patients undergoing
radiotherapy for anal canal cancer and conduct dosimetry and accuracy research. Methods 3D printing technology was used to
print tissue compensation that fit well with the patient’s skin, and a variety of radiotherapy schemes were designed for dosimetry
comparison and verification. Then, a simulated human body model was used to verify the dosimetry accuracy of the superficial tumor
site. Results The normal tissues of the four groups of radiotherapy plans all could meet the clinical dose requirements and there was
no statistical difference; The coverage of the target area D98 was (64.8±1.6), (64.5±1.67), (64.6±1.3), (64.7±1.4) Gy, respectively,
also met the clinical requirements and there was no statistical difference. The maximum dose Dmax in the target region was (73.7±2.1),
(69.7±1.3), (68.9±2.3), (68.6±1.6) Gy, respectively, and there was a statistical difference in the highest dose of the target area. The
results of the film dose verification showed that for the radiotherapy plan without compensation material and the radiotherapy plan
with ordinary compensation, the planned dose of the superficial part of the tumor and the actual measured dose had large deviations,
which were 37.1% and 12.6%, respectively. The 3D printed individuals compensation had the smallest deviation, which was 6.9%.
Conclusion The 3D printed individualized tissue compensation meets the requirements of radiotherapy for anal canal cancer, with
small air gaps and good fit with the patient’s skin, which can truly increase the dose of superficial anal cancer.
曾彪1，窦钰姣2，谭剑锋1，骆龙军1，黄仕雄1，周琼辉1，曾德高1，徐诗磊1，朱婉琳1，张九堂1. 3D打印个体化补偿物在肛管癌放疗中的研究[J]. 中国医疗设备, 2022, 37(4): 136-139.
ZENG Biao1, DOU Yujiao2, TAN Jianfeng1, LUO Longjun1, HUANG Shixiong1, ZHOU Qionghui1, ZENG Degao1,
XU Shilei1, ZHU Wanlin1, ZHANG Jiutang1. Research of 3D Printing Individualized Compensation in Radiotherapy of Anal Canal Cancer. China Medical Devices, 2022, 37(4): 136-139.
