Scan-Rescan Reproducibility of 3D Joint Intra- and Extra-Cranial Vessel Wall
Magnetic Resonance Imaging for Atherosclerosis Evaluation
SHEN Mi1, GAO Peiyi1,2, DU Kang1, CHEN Shuo3
1.Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China; 2.Beijing Neurosurgical Institute,
Beijing 100050, China; 3.Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China
Abstract：Objective To evaluate the reproducibility of scan-rescan reproducibility of 3D joint intra- and extra-cranial vessel wall
magnetic resonance imaging for atherosclerosis characteristics (morphology and component) evaluation. Methods A total of 10
symptomatic patients with ischemic infarction in middle cerebral artery (MCA) region with carotid or MCA atherosclerosis were
recruited. All patients were scanned twice within one month with 3D joint intra- and extra-cranial vessel wall imaging. Plaque
presence, lumen area (LA), wall area (WA), maximum wall thickness (MWT), stenosis, plaque area (PA), plaque distribution, as well
as plaque components such as intraplaque hemorrhage (IPH), calcification (CA), ulceration of carotid, plaque distribution (IPH) of
MCA were evaluated for bilateral common carotid artery (CCA), carotid Bulb, C1 and C2-C7 segments of internal carotid artery and
M1 segment of MCA. Results After exclusion of 1 patient with poor image quality, 72 carotid segments and 18 MCA segments from
9 patients were evaluated. A total of 14 carotid and 8 MCA plaques were identified. Good correlation (ICC>0.75) were found in LA,
WA, MWT, stenosis and PA evaluation. Near-perfect (Kappa>0.8) agreement was found in presence, CA and ulceration of carotid
plaque, and presence, distribution and IPH of MCA plaque. Substantial agreement (0.8>Kappa>0.6) agreement were found in carotid
IPH detection. Conclusion This study shows high reproducibility of 3D joint intra- and extra-cranial vessel wall magnetic resonance
imaging for atherosclerosis evaluation which has good clinical application prospects.
沈宓1，高培毅1,2，杜康1，陈硕3. 3D颅颈联合血管壁成像评估动脉粥样硬化的可重复性研究[J]. 中国医疗设备, 2018, 33(9): 32-36.
SHEN Mi1, GAO Peiyi1,2, DU Kang1, CHEN Shuo3. Scan-Rescan Reproducibility of 3D Joint Intra- and Extra-Cranial Vessel Wall
Magnetic Resonance Imaging for Atherosclerosis Evaluation. China Medical Devices, 2018, 33(9): 32-36.
