Abstract:Objective To investigate the efficacy and security of High Intensity Focused Ultrasound (HIFU) in treating patients with advanced pancreatic carcinoma. Methods 20 newly received cases of advanced pancreatic carcinoma with HIFU was treated. The curative effect of HIFU was observed by testing the function of major organs, examining the tumor volume changes with CT and ultrasound, and observing the serum level of CA19-9, CA242 and other indicators. Results After treatment, the pain symptoms were relieved significantly in nearly 85% of the patients. Results of 7-21d imaging examination showed that compared with patients before treatment, tumor volume in 9 cases (45%) was decreased, in 8 cases (40%) was almost changeless and in 3 cases (15%) was increased among patients after treatment. Results of CT enhanced scan showed that tumors in 6 cases did not have significant enhancement and in 14 cases had regional enhancement. The latter indicated the existence of blood flow and suggested that tumors had not been destroyed by heat and more treatment were needed. The concentration of biochemical markers such as CA19-9、CA242 was decreased and no significant complications were appeared in patients after treatment in the near future. Conclusion As a safe treatment method, HIFU treatment can significantly relieve sufferings, improve life quality and extend life span of patients with advanced pancreatic carcinoma.
张涛,刘在照. 高强度超声聚焦治疗晚期胰腺癌20例的疗效分析[J]. 中国医疗设备, 2013, 28(7): 109-112.
ZHANG Tao, LIU Zai-zhao. A Study about Curative Effect of High Intensity Focused Ultrasound on 20 Patients with Advanced Pancreatic Cancer. China Medical Devices, 2013, 28(7): 109-112.
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