Diagnostic Value of Conventional MRI Sequence+DWI+SWI Combined with NSE in
Adult Hypoglycemic Encephalopathy
GUI Hong1，CHEN Wen1，WANG Kejun1，ZHAO Yansheng2
1. Medical Imaging Center, Taihe Hospital (Affiliated Taihe Hospital of Hubei University of Medicine), Shiyan Hubei 442000, China丨
2. Radiology Center, Shiyan Renmin Hospital ( Renmin Hospital Affiliated to Hubei University of Medicine), Shiyan Hubei 442000, China
Abstract：Objective To explore the diagnostic value of conventional magnetic resonance imaging (MRI) sequence + diffusion
weighted imaging (DWI) + susceptibility weighted imaging (SWI) combined with neuron specific enolase (NSE) in adult
hypoglycemic encephalopathy. Methods From August 2018 to August 2019, 60 patients with hypoglycemia encephalopathy
confirmed by pathological examination were selected. All patients were examined by conventional MRI sequence + DWI+ SWI,
conventional MRI sequence + DWI + SWI combined with NSE. At the same time, 60 peoples were selected for physical examination
in our hospital as a healthy group, and MRI routine sequence +DWI+SWI combined with NSE was used to detect the healthy
group. C-reactive protein (CRP), NSE and S-100B were detected by enzyme-linked immunosorbent assay. The detection, missed
diagnosis, misdiagnosis rate and diagnostic efficacy of the two methods were compared. Results Compared with the healthy
group, the levels of CRP, NSE and S-100B in the hypoglycemic encephalopathy group increased from 0.95, 2.03 and 6.31 to
18.71, 24.41 and 46.51 (P<0.05). Compared with the healthy group, the basal ganglia apparent dispersion coefficient value of the
hypoglycemia encephalopathy group decreased from 1.09 to 0.45, and the SDC value of the compression part of the corpus callosum
decreased from 0.99 to 0.35, with statistically significant differences (P<0.05). The diagnostic sensitivity, specificity and accuracy
of conventional MRI sequence + DWI + SWI in combined with NSE were higher than those of conventional high-frequency MRI
sequence +DWI+SWI (P<0.05). The rate of missed diagnosis and misdiagnosis of conventional MRI+DWI+SWI combined with
NSE was lower than that of high frequency conventional high-frequency MRI+DWI +SWI (P<0.05). Conclusion Compared with
the conventional MRI sequence + DWI + SWI detection, conventional MRI sequence+ DWI + SWI combined with NSE detection
has higher detection rate, diagnostic sensitivity, accuracy and better diagnostic efficiency.
桂红1，陈文1，王克军1，赵艳生2. MRI常规序列+DWI+SWI联合NSE对成人低血糖脑病的诊断价值研究[J]. 中国医疗设备, 2021, 36(8): 74-79.
GUI Hong1，CHEN Wen1，WANG Kejun1，ZHAO Yansheng2. Diagnostic Value of Conventional MRI Sequence+DWI+SWI Combined with NSE in
Adult Hypoglycemic Encephalopathy. China Medical Devices, 2021, 36(8): 74-79.
