Abstract：Objective To investigate the correlation between the measurement value of diffusion tensor imaging (DTI) sequence and the degree of nerve fiber tract damage with clinical manifestations of cervical spondylotic myelopathy. Methods The clinical data of 52 patients with cervical spondylosis in our hospital from September 2018 to August 2019 were retrospectively analyzed. All patients underwent conventional MRI sequence, DTI sequence and 3D-BRAVO sequence scanning. According to the clinical manifestations of the patients, the Japanese Orthopaedic Association (JOA) score was made and divided into mild group, moderate group and severe group. SPSS was used to analyze the statistical significance of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) in the three groups. Spearman analysis was used to observe the correlation between JOA and DTI data. Results The measured FA values of the spinal cord in the three groups of mild, moderate and severe compression were 0.65±0.03, 0.51±0.03, 0.42±0.02, which were significantly different (F=290.44, P<0.05). The ADC values of the three groups were 1.02±0.14, 1.30±0.25, 1.19±0.29, and there were significant differences in comparison (F=10.509, P<0.05). The FA value of the test for homogeneity of variance was significant 0.097 (P>0.05), and the least significant difference method was selected, and the difference between the two comparisons was statistically significant (P<0.05), and the significance of the ADC value due to the homogeneity of variance test was 0.013 (P<0.05). There was a positive correlation between the JOA score value and the average FA value of each group (r=0.972, P<0.05). Conclusion The FA value measured by DTI is positively correlated with the clinical FOA score. The higher the FA value, the lower the damage to the cervical spinal cord fiber bundle. Therefore, DTI fiber bundle imaging can more intuitively display the damage of the cervical cord fiber bundle.
Bourgonjon B,Duerinck J,Moens M,et al.Comparison of the effect of anterior and posterior neurosurgical treatment for cervical spondylotic myelopathy: a clinical outcome[J].Acta Neurol Belg,2019,119(4):585-593.
