Abstract：Objective To explore the effect of different registration methods on dose distribution during radiotherapy for nasopharyngeal carcinoma. Methods Twenty patients with nasopharyngeal carcinoma radiotherapy were selected as the study subjects, and registration errors were obtained by using three different registration methods: allover, head and neck. The results were fed into the original treatment plan to generate the registration error simulation plan, and the target area and organ at risk volume dose parameters were obtained and compared with the original plan. The dose deviation results were recorded as the relative deviation value. Results 132 CBCT
scans were performed in 20 patients. The registration errors of allover versus head registration methods had no statistical significance but the registration errors of allover versus neck registration methods had statistical difference (P<0.05). The relative dose deviation of the target of allover vs neck registration methods had statistical difference (P<0.05) in GTVnx, GTVnd L, GTVnd R, PTV1. For the perspective of the relative dose deviation values for GTVnx, the overall of it within ±3% accounted for 81.2%, in which the head accounted for 80.3%, and the neck accounted for 65.9%. Compared with the allover. the relative dose deviation of the target of neck is generally reduced, and the value changed was large, there was a statistical difference (P<0.05). The relative dose deviation of organs
at risk changed differently and had no statistical significance (P>0.05). Conclusion The effect of cervical fixation of nasopharyngeal
carcinoma is not ideal, and neck registration has a great influence on the actual dose deviation, which needs to be noted. When the errors between neck and head are large, the registration errors of head shall prevai.
丘敏敏，钟嘉健，李敏，林泽煌，闵蒙真，肖振华，邓永锦. 鼻咽癌调强放疗摆位不同配准方式对实际剂量学的影响[J]. 中国医疗设备, 2020, 35(11): 94-97.
QIU Minmin, ZHONG Jiajian, LI Min, LIN Zehuang, MIN Mengzhen, XIAO Zhenhua, DENGYongjin. Different Registration Methods for Volumetric Modulated Arc Therapy in the Nasopharyngeal Carcinoma: Effect on Dose Distribution. China Medical Devices, 2020, 35(11): 94-97.
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