Photoacoustic Imaging Technology for Clinical Applications
LIN Riqiang, LENG Ji, CHEN Jingqin, LIU Chengbo, GONG Xiaojing, SONG Liang
Research Laboratory for Biomedical Optics and Molecular Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy
of Sciences, Shenzhen Guangdong 518055, China
Abstract：Photoacoustic imaging is a novel imaging modality that utilizes pulsed laser to illuminate samples and ultrasonic
transducers for detection of the laser absorption generated ultrasonic/photoacoustic waves. Benefited from its high optical contrast
and acoustic resolution at depth, as well as the capability of acquiring optical spectral information, photoacoustic imaging allows for
structural and functional imaging of the biological relevant information such as hemoglobin concentration, blood oxygen metabolism,
and lipid with high specificity, and is able to capture the corresponding physiological feature dynamics with high sensitivity. In
terms of the imaging system, photoacoustic imaging manifests a variety of embodiments catering the multi-scale biomedical
imaging needs. The above mentioned features and capabilities enable extensive biomedical application potentials of this imaging
modality in both clinical diagnosis and pathological analysis, such as malignant tumor detection, atherosclerotic plaque assessment,
and microcirculation abnormality diagnosis. Therefore, it is attracting more and more attention and interests in a wide range ofbiomedical research areas. This article presented the recent progress of photoacoustic technology development and application studies
in our group in the fields of microvascular imaging, intravascular imaging, gastrointestinal endoscopic imaging, and sentinel lymph
node imaging.
林日强，冷吉，陈敬钦，刘成波，龚小竞，宋亮. 面向临床应用的光声成像技术[J]. 中国医疗设备, 2018, 33(1): 1-5.
LIN Riqiang, LENG Ji, CHEN Jingqin, LIU Chengbo, GONG Xiaojing, SONG Liang. Photoacoustic Imaging Technology for Clinical Applications. China Medical Devices, 2018, 33(1): 1-5.
