Abstract:Objective To analyze the characteristics of contrast-enhanced ultrasound (CEUS) of primary
small hepatic carcinoma (PSHC) with different differentiated degrees so as to investigate the clinical
effectiveness of application of CEUS in diagnosis and classification of this disease. Methods A
retrospective analysis of CEUS data of 47 patients with PSHC confirmed by surgery and pathology was
made. Quantitative parameter of CEUS for PSHC with different differentiated degrees was compared.
Enhanced intensity among differentiated degree groups was compared in arterial phase, portal phase
and delayed phase. Compared to pathological examinations, the diagnosis accordance rate of CEUS
was analyzed. Results According to the postoperative pathological results of 47 patients, 22 cases were
well differentiated, 20 cases were moderately differentiated and 5 cases were poorly differentiated. Both
the arrival time and peak time were similar in PSHC with different degrees of differentiation, without
statistically significant difference (P>0.05), but with statistically significant difference compared with
the time to contrast washout (P<0.05). There was significant difference of enhanced intensity among
differentiated degree groups in the portal phase and delayed phase (P<0.05). As the differentiated
degree grew, the proportion of low enhanced intensity increased. 43 patients with PSHC were correctly
diagnosed by CEUS, with a pathological diagnostic accordance rate of 91.49%. Conclusion Certain
differences were seen between the CEUS characteristics of PSHC with different differentiated degrees .
CEUS provided important references for clinical diagnosis and classification of PSHC.
米波. 超声造影在不同分化程度的原发性小肝癌诊断中的应用研究[J]. 中国医疗设备, 2016, 31(8): 47-50.
MI Bo. Study on the Application of Contrast-Enhanced Ultrasound in Diagnosis of
Primary Small Hepatic Carcinoma with Different Degrees of Differentiation. China Medical Devices, 2016, 31(8): 47-50.