Abstract:Objective To examine the association between Lipoprotein(a) (Lp(a)) levels and carotid
vulnerable plaques. Methods A total of 124 carotid plaques patients who were treated in our hospital
between June 2015 and January 2016 were enrolled in this study. The carotid plaques were classified into
three types according to respective features: soft plaque, fibrous plaque and calcified plaque. Serum Lp(a)
levels were measured by immunoturbidimetric assay. According to the median, Lp(a) was divided into
high level group (Group A) and low level group (Group B), then the incidence of carotid plaque between
the two groups was compared. Results The prevalence of soft plaque was significantly higher, fibrous
plaque was significantly lower in Group A than Group B (P<0.05). There was no significant difference in
the incidence of calcified plaques between the two groups (P>0.05). Conclusion These results suggested
that high-level Lp(a) might be closely associated with carotid vulnerable plaques. Lowering Lp (a) level
was helpful to stabilize the plaque.
刘艳. 脂蛋白a与颈动脉易损斑块的相关性研究[J]. 中国医疗设备, 2016, 31(7): 64-65.
LIU Yan. Study on the Relationship between Lipoprotein(a) and Carotid Vulnerable
Plaques. China Medical Devices, 2016, 31(7): 64-65.