Abstract：Objective To study the relationship between third trimester umbilical artery S/D (Systolic/
Diastolic Ratio) value and fetal growth & development in high-risk pregnancy. Methods The study was
conducted in the hospital from July 2013 to July 2014, including 40 patients with GDM (Gestational
Diabetes Mellitus), 63 patients with HDP (Hypertension Disorder Complicating Pregnancy) and 73
pregnant women without complications (Control Group). The age, gestational weeks, MAP (Mean
Arterial Pressure), third trimester S/D ratio, genetic tendency, body index, height, weight and head
circumference of neonatus and the Neonatal Apgar score were recorded, and ZLI (Zhang Lu Index) and
RI (Raul Index) were calculated for comparison between three groups. Results S/D value was negatively
correlated with ZLI and RI. The umbilical artery blood S/D value of GDM Group and HDP Group were
higher than that of Control Group with the same gestational weeks, and the control of blood pressure
level in HDP Group affected S/D value, ZLI and RI. The increased S/D value for pregnancy more
than 39 weeks might have adverse effects on fetal and perinatal prognosis. GDM Group with a family
history of diabetes and HDP Group with a family history of high blood pressure would further affect
the perinatal growth. In reference with the standards of neonatal physical development, ZLI was more
accurate than RI in evaluating the condition of the newborn. Whether S/D=2.5 was taken as the warning
value for high-risk pregnancy in late pregnancy (over 35 weeks) remained to be validated through a large
number of data. Conclusion The late pregnancy umbilical artery S/D value of high-risk pregnant women
reflected the fetal intrauterine growth. The neonatal body mass index, ZLI and RI were correlated with
the total value of S/D, which showed that the S/D value had a certain role in prognosis. The coefficient of
determination of SD and ZLI was two times of SD and RI, suggesting that ZLI and SD were more closely
than RI and SD. Therefore, the umbilical artery S/D value of the pregnant women at high risk could be
used to guide the clinical evaluation of fetal growth and development in the termination of pregnancy.
程娟娟a，冉文军b. 高危妊娠孕晚期脐动脉S/D值与胎儿综合生长发育情况的关系研究[J]. 中国医疗设备, 2016, 31(7): 36-40.
CHENG Juan-juana,RAN Wen-junb. Study on the Relationship between the Third Trimester Umbilical Artery
S/D Value and Fetal Growth & Development in High-Risk Pregnancy. China Medical Devices, 2016, 31(7): 36-40.
