Comparison of Ultrasound-guided Fine-needle Aspirtion and Coreneedle
Biopsy in Diagnosis of Thyroid Nodules Bigger than 10 mm in
Maximum Diameter
WANG Ying, CHEN Song-wang
Department of Functional Examination,
Nanjing Hospital Affiliated to Nanjing Medical
University (Nanjing First Hospital), Nanjing
Jiangsu 210006, China
Abstract：Objective To evaluate the accuracy and safety of ultrasound-guided fine-needle aspiration
（US-FNA）and core-needle biopsy (US-CNB) for the separate and joint diagnosis of thyroid nodules
bigger than 10 mm in maximum diameter. Methods 36 cases of thyroid nodules bigger than 10 mm
in maximum diameter were examined by both US-FNA and US-CNB. Retrospective analysis was
conducted on two diagnostic methods in terms of the diagnostic coicidence rate with pathologic diagnosis
and complication rate. Results For the 36 cases of thyroid nodules, US-FNA and US-CNB showed
diagnostic coincidence rate of 75% and 94.44% respectively, and difference was statistically significant
（P＜0.05). The joint diagnosis by both US-FNA and US-CNB showed diagnostic coincidence rate
of 97.22%, but difference was not statistically significant when compared with diagnosis by US-CNB
alone. Sensitivity and negative predictive value of US-FNA were 66.67% and 50% respectively in
comparison with US-CNB’s 92.59% and 81.82% and the joint diagnosis method’s 96.30% and 90%.
The specificity and positive predictive value of these two diagnosis methods were both 100%. Only
the sensitivity between US-FNA and US-CNB showed statistically significant different (P＜0.05). No
complications occurred in the two puncture methods. Conclusion US-CNB was better puncture method
for preoperative diagnosis of thyroid nodules bigger than 10 mm in maximum diameter, and it should be
chosen as the preferred method for biopsy when the nodules were larger.
王颖，陈松旺. 超声引导下细针抽吸诊断与粗针穿刺活检对直径大于10 mm甲状腺结节的诊断价值的比较[J]. 中国医疗设备, 2016, 31(5): 93-95.
WANG Ying, CHEN Song-wang. Comparison of Ultrasound-guided Fine-needle Aspirtion and Coreneedle
Biopsy in Diagnosis of Thyroid Nodules Bigger than 10 mm in
Maximum Diameter. China Medical Devices, 2016, 31(5): 93-95.
