Abstract：Semiconductor quantum dots (QDs) are tiny light-emitting particles on the nano-meter scale, and have been widely used for bio-medical applications due to their unique optical and electronic properties. Compared with traditional organic dyes and fluorescent proteins, they have size-tunable light emission, superior signal brightness, photo-bleaching resistance, and broad absorption spectra for simultaneous excitation of multiple fluorescence colors. When conjugated with targeting ligands such as antibodies, peptides or small molecules, QDs can be used to target tumor bio-markers as well as tumor vasculatures with high affinity and specificity. This paper summarizes some of the applications of QDs for cancer diagnosis and imaging. And it also discusses the restrictions for clinical applications and gives some perspectives for the future applications of QDs.
王贺宁，孟祥溪，周克迪，任秋实，孙红芳. 分子影像探针—量子点在癌症成像和早期检测中的应用[J]. 中国医疗设备, 2015, 30(4): 7-10.
WANG He-ning, MENG Xiang-xi, ZHOU Ke-di, REN Qiu-shi, SUN Hong-fang. A Novel Molecular Imaging Probe: Application of Quantum Dots in Cancer Imaging &Early Diagnosis. China Medical Devices, 2015, 30(4): 7-10.
