Abstract:Objective To test and evaluate the performance of SYSMEX XT-4000i hematology analyzer. Methods Clinical blood samples, body fluid samples and quality control materials were used to test and evaluate the background counting, contamination rate, precision (within-run precision, within-day precision), linear range, accuracy, and the contrast between XT-4000i machines. Results The background counting tested by XT-4000i was lower than the specified requirements designed by the manufacturer. Using the XT-4000i to test the WBC, RBC, HGB and PLT has advantages of low contamination rate, and high precision, linear range and accuracy, as well as strong correlation between differential leukocyte counting and microscope classification. The results of testing the WBC, RBC and differential leukocyte manual counting by XT-4000i are highly related. Conclusion The XT-4000i hematology analyzer has good performance to meet the requirements of clinical routine detections of blood and body fluid samples.
CLSI.alidation.Verification,and Quality of Automated Hematology.lyzers.CLSI document H26-A2[S]. Wayne,Pa.:Clinical and Laboratory Standards Insyitute.2010.
[2]
WS/T406-2012,临床血液学检验常规项目分析质量要求[S].
[4]
YY/T0653-2008,血液分析仪[S].
[5]
Amundsen EK, Henriksson CE, Holthe MR, Urdal P. Is the blood basophil count sufficiently precise, accurate, and specific?: three automated hematology instruments and flow cytometry compared[J]. Am J Clin Pathol. 2012 Jan;137(1):86-92.