Research on Improved Methods and Auxiliary Devices for Precise Positioning of Breast
Tumors Based on 3D Printing Technology
YANG Ying1，QIN Xin2，ZHOU Xuefang2，ZHANG Ying1，XU Fangyuan1，LIU Shilu1，FAN Jinlei1，WANG Chuanbing1,3
1. School of Medical Imaging, Nanjing Medical University, Nanjing Jiangsu 210029, China| 2. Jiangsu Ideal Medical Science&Technology Co., Ltd., Zhangjiagang Jiangsu 215625, China| 3. Department of Radiology, The First Affiliated Hospital of
Nanjing Medical University, Nanjing Jiangsu 210029, China
Abstract：Objective To provide a new positioning method and auxiliary device for precise surgical resection of breast tumor. Methods 13 patients with breast cancer were selected. Before MRI examination, patients wore positioning aids to obtain prone position MR images similar to breast supine position, and then imported Mimics and 3-Matic software to design 3D reconstruction of breast and 3D positioning guide of tumor. Before operation, the guide was placed on the surface of breast, and methylene blue solution was injected to dye the tumor edge to locate the tumor edge. Results The median distance from tumor edge to tissue cutting edge was measured in 13 patients. And all patients had clear cut edge. The median distance from tumor edge to tissue resection edge using this improved technique was (1.6±0.05) cm. That of Korea’s existing method was (1.86±0.11) cm (t =-7.1, P < 0.001). And the comparison between the two was statistically significant. Conclusion The use of positioning aids can reduce the number of breast MR images in supine position, and the positioning guide can accurately locate the tumor edge. This method does not increase the extra pain of patients, reduces the operation time, and ensures the accurate tumor resection. It can lay a foundation for accurate guidance of breast tumor intraoperative localization and breast conserving surgery.
杨颖1，秦鑫2，周雪芳2，张颖1，徐方园1，刘仕露1，范金蕾1，王传兵1,3. 基于3D打印技术的乳腺肿瘤精准定位改进方法及辅助装置的研究[J]. 中国医疗设备, 2020, 35(10): 164-167.
YANG Ying1，QIN Xin2，ZHOU Xuefang2，ZHANG Ying1，XU Fangyuan1，LIU Shilu1，FAN Jinlei1，WANG Chuanbing1,3. Research on Improved Methods and Auxiliary Devices for Precise Positioning of Breast
Tumors Based on 3D Printing Technology. China Medical Devices, 2020, 35(10): 164-167.
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