Detecting and Analyzing System for Brachial Artery Endothelial Function
LI Si-qi1, SHEN Hua1,2,ZHU Yong1, LIANG Shun1,QIN Kai-rong1
1.Department of Biomedical Engineering,
Faculty of Electronic Information and
Electrical Engineering, Dalian University
of Technology, Dalian Liaoning 116024,
China; 2.Department of Electronic
Engineering, Dalian Neusoft University
of Information, Dalian Liaoning 116023,
China
Abstract：The damage or dysfunction of arterial endothelial function is the primary performance at the
early stage of atherosclerosis. Quantitative evaluation of brachial artery endothelial function is helpful to
discover the cardiovascular dysfunction in time, thus provides some evidence for the early diagnosis and
treatment of cardiovascular and cerebrovascular diseases. To date, brachial artery endothelial function is
evaluated at clinic by measuring the brachial flow-mediated vasodilation (FMD) with a Color Doppler
Ultrasonography. Although the accuracy and resolution of this method are much higher, its equipment is
relatively expensive, and its operation is very complicated. In this study, a detecting and analyzing system
is proposed for evaluating brachial artery endothelial function based on forearm biological electrical
impedance signal. By detecting forearm biological impedance signal before and after brachial FMD, the
characteristic parameters of biological electro-impedance signals, including characteristic frequency,
absolute energy, average amplitude and their relative alteration rate, are calculated using wavelet analysis
technology. As the changes in the forearm biological electro-impedance before and after FMD are mainly
caused by the changes in the brachial arterial diameter, the detecting and analyzing system of forearm
biological electro-impedance signal would provide a new idea for evaluating quantitatively brachial
artery endothelial function. In comparison with existing methods at clinic, the detecting and analyzing
system of forearm biological electro-impedance signal is detection-simpler, cheaper, more practical
and convenient, it can not only be used in the family or community medicine, but also realize on-line
detection and provide with a methodology base for further development of the intelligent and wearable
electrical impedance analyzer for monitoring arterial function.
李思琦1，申华1,2，朱勇1，梁舜1，覃开蓉1. 一种评估肱动脉内皮功能的电阻抗信号检测与分析系统[J]. 中国医疗设备, 2016, 31(9): 9-13.
LI Si-qi1, SHEN Hua1,2,ZHU Yong1, LIANG Shun1,QIN Kai-rong1. Detecting and Analyzing System for Brachial Artery Endothelial Function. China Medical Devices, 2016, 31(9): 9-13.
