目的 探讨产前彩超在检测胎儿脐带血管数目，预测胎儿发育异常几率和妊娠结局中的应 用。方法 收集2005年3月~2013年12月在本院行产前彩超检查的病例，检测其胎儿脐带血管数目， 分析单脐动脉合并畸形的类型、与染色体异常的相关性以及妊娠结局。结果 超声诊断单脐动脉 72例，其中左侧缺失44例，右侧缺失28例。单纯单脐动脉无合并其他畸形53例，合并其他畸形19 例。其中13例行染色体检查，发现染色体异常4例，包括18-三体综合征2例、13-三体综合征1例、 21-三体综合征各1例，均合并其他畸形。结论 大部分单纯单脐动脉胎儿妊娠结局良好；合并其他 畸形的单脐动脉胎儿染色体异常发生率高。术前彩超在检测胎儿脐带血管数目，预测胎儿发育异 常中具有重要临床价值。

Objective To evaluate the application of prenatal color Doppler ultrasound in detecting single umbilical artery (SUA) so as to predict the rate of fetal congenital malformation and pregnancy outcomes. Methods Cases that underwent prenatal color ultrasound from March 2005 to December 2013 were selected. The number of umbilical cords was examined to analyze types of SUA-associated abnormalities, the relationship between SUA and chromosome anomalies, and pregnancy outcomes. Results SUA was diagnosed in 72 cases. The left umbilical artery was absent in 44 cases; the right umbilical artery was absent in 28 cases. SUA as an isolated finding occurred in 53 fetuses; 19 cases had associated malformations. Chromosomal defects were diagnosed in 8 of 13 cases that had accepted karyotype examination, including two cases of trisomy 18, one case of trisomy 13, one case of trisomy 21. Conclusion Most cases of fetuses with isolated SUA showed good pregnancy outcome. Chromosomal abnormalities happened more frequently in SUA accompanied with other anomalies. Prenatal color Doppler ultrasonography was of important clinical value in examining number of umbilical arteries and in prediction of abnormal fetal growth.