目的 新一代一体化设计的正电子发射断层扫描/磁共振（PET/MR）将PET探测器嵌入MR设备中，实现PET和MR两个探测器同空间同时采集，但新设备结构中PET部分在日常临床工作的稳定性有待进一步研究。本研究追踪装机五年后近16个月数字一体化uPMR790型PET/MR设备PET有源质控的相关数据，探讨数字一体化PET/MR设备在临床使用中的稳定性及PET有源质控参数间的影响因素。方法 在临床应用的条件下，依据相关设备制造商发布的设备日常质量保证（DQA）内容，对uPMR790进行有源质量控制，统计分析其2023年1月至2024年5月共72周有源质控的系统测试参数：系统温度和电压、系统查找表（LUT）、采集系统（CMap）、飞行时间（TOF）和系统能量的状态漂移区间。使用Spearman相关性分析、Mann-WhitneyU检验对系统质控参数进行分析，应用多元线性回归分析探讨TOF漂移程度的影响因素。结果 72次PET/MR有源质控总体通过率为100%，TOF状态漂移LUT状态漂移（r=0.614,P<0.001）呈正相关，与系统最高温度（r=-0.736,P<0.001）呈负相关；与系统采集CMap状态改变存在分布差异（Z=4.872，P<0.001）。多元线性回归分析显示，LUT漂移（β=0.705，p<0.001）、系统采集CMap（β=0.131，P=0.031）对TOF漂移程度具有正向影响，系统最高温度（β=-0.263，p<0.001）对TOF漂移程度具有负向影响。结论 数字一体化uPMR790在临床使用5年后，近16个月PET有源质控的测试参数均在正常范围内，设备在日常临床应用中运行稳定。但须警惕有源质控中PET探测器相关参数可能发生的漂移，并结合风险提示进行定期监测，以确保设备长期稳定性和诊断结果的可靠性。

Objective The next-generation integrated design of Positron Emission Tomography/Magnetic Resonance (PET/MR) combines PET detectors into the MR device, enabling simultaneous data collection from both detectors in the same space. However, the stability of the PET component in this new device structure during daily clinical operations requires further investigation. This study tracks nearly 16 months of source quality control data from the digital integrated uPMR 790 PET/MR system, five years after installation, to explore the stability of the digital integrated PET/MR system in clinical use and the influencing factors between PET source quality control parameters. Methods Under clinical application conditions, source quality control of the uPMR 790 system was conducted based on the daily quality assurance (DQA) guidelines issued by the equipment manufacturer. Data from 72 weeks of source quality control system tests from January 2023 to May 2024 were collected, including system temperature and voltage, Look-Up Table (LUT), collection system (CMap), Time of Flight (TOF), and system energy state drift. Spearman correlation analysis and Mann-Whitney U tests were used to analyze the system quality control parameters. Multiple linear regression analysis was conducted to explore the influencing factors of TOF drift. Results The overall pass rate for 72 PET/MR source quality control tests was 100%. TOF state drift showed a positive correlation with LUT state drift (r = 0.614, P < 0.001) and a negative correlation with the system's maximum temperature (r = -0.736, P < 0.001). There were distributional differences between TOF state drift and changes in the system's acquisition CMap state (Z = 4.872, P < 0.001). Multiple linear regression analysis revealed that LUT drift (β = 0.705, P < 0.001) and system acquisition CMap (β = 0.131, P = 0.031) had positive effects on the degree of TOF drift, while the system's maximum temperature (β = -0.263, P < 0.001) had a negative effect on the degree of TOF drift. Conclusion After five years of clinical use, Over the past 16 months, the testing parameters for PET source quality control have remained within normal ranges, and the equipment has demonstrated stable performance in daily clinical applications. However, attention should be paid to potential drifts in parameters related to the PET detectors during source quality control. Regular monitoring, combined with risk alerts, is essential to ensure the long-term stability of the equipment and the reliability of diagnostic outcomes.