摘要目的 探讨磁共振多层同时成像技术(MultiBand SENSE,MB SENSE)在腰骶丛神经弥散张量成像(Diffusion Tensor Imaging,DTI)中的应用价值。方法 招募13名健康志愿者(年龄范围11~70岁,平均33.42±16.51岁)在3T MRI上进行常规DTI扫描(SENSE 1.6)和MB SENSE的DTI扫描(MB SENSE 2和3)。利用弥散张量纤维束造影(Diffusion Tensor Tractography,DTT)清晰地显示整个腰根神经,并在DTI图像上测量腰骶丛神经(两侧L3~S1)的平均各向异性分数(Fractional Anisotropy,FA)值。然后,将不同腰骶丛神经SENSE 1.6、MB SENSE 2、MB SENSE 3的FA值采用Friedman检验进行比较。结果 同一腰节段左右侧神经无差异(P>0.05),而且不同腰骶丛神经FA值在SENSE 1.6、MB SENSE 2、 MB SENSE 3中的差异无统计学意义(P=0.498、0.451、0.373、0.125、0.189、0.886、0.379、0.614)。基于SENSE 1.6和MB SENSE 2的腰根神经L3至S1的全长使用DTT可清晰显示,而基于MB SENSE 3的神经束远端较差。而且,MB SENSE技术DTI比传统DTI扫描时间缩短50%。结论 基于MB SENSE技术的弥散张量成像可以显示和提供人体腰骶丛的定量信息。本研究建议采用MB SENSE 2对正常腰骶丛神经进行扫描。
Abstract:Objective To explore the application value of MultiBand SENSE (MB SENSE) in the lumbosacral plexus nerve diffusion tensor imaging (DTI). Methods Thirteen healthy volunteers (aged 11-70 years, mean 33.42 ± 16.51 years) were recruited for DTI scan (SENSE 1.6) and DTI scan (MB SENSE 2, 3) on 3T MRI. Diffusion tensor tractography (DTT) was used to clearly display the whole lumbosacral nerve, and the average FA value of lumbosacral plexus (L3-S1) was measured on DTI images. Then, the fractional anisotropy (FA) values of different lumbosacral plexus nerve SENSE 1.6, MB SENSE 2, MB SENSE 3 were compared by Friedman test. Results There was no significant difference between left and right nerves in the same lumbar segment (P>0.05), and the FA values of different lumbosacral plexus nerves in SENSE 1.6, MB SENSE 2, MB SENSE 3 had no statistical significance (P=0.498, 0.451, 0.373, 0.125, 0.189, 0.886, 0.379, 0.614). The full length of L3 to S1 of lumbar root nerve based on SENSE 1.6 and MB SENSE 2 can be clearly displayed by DTT,while the distal end of nerve bundle based on MB SENSE 3 was poor. Moreover, the scan time of MB sense DTI was 50% shorter than that of traditional DTI. Conclusion Diffusion tensor imaging based on MB SENSE technology can display and provide quantitative information of human lumbar fascicles. In this study, we suggest that MB SENSE 2 should be used to scan the normal lumbosacral plexus.
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