Abstract:Objective Often the traditional Thyroid Uptake System (TUS) cannot accurately measure taken
technetium rate. This paper aimed to discusses the effectiveness of Single Photon Emission Computed
Tomography (SPECT)/CT after injection of 99mTcO4 in detecting thyroid function abnormalities.
Methods 60 patients of thyroid inspectors were analyzed retrospectively, including 20 cases of diffuse
toxic goiter (Graves disease), 15 cases of thyroiditis and 25 cases of normal thyroid function. All patients
were administered SPECT/CT after injection of 99mTcO4, calculating thyroid uptake rate and Standardized
Uptake Value (SUV), 20 Graves disease and 15 thyroiditis patients accept traditional determination of
TUS in the same period. Results SPECT/CT quantitative evaluation parameters (thyroid uptake rate,
average and maximum of standard intake) largest in Graves disease, followed by thyroiditis, minimum
thyroid function in normal (P<0.001); TUS significantly overestimated the thyroid uptake rate compared
with SPECT/CT (P<0.001) because other 99mTcO4 sources in addition to thyroid contributed to the
thyroid uptake rate result by TUS, whereas the SPECT/CT quantitative evaluation parameter with thyroid
hormone levels has better correlation (P<0.05). Conclusion Quantitative SPECT/CT is more accurate
than conventional TUS for measuring 99mTcO4 thyroid uptake rate, also has important clinical value in the
diagnosis of thyroid function disease.
刘任从,张乐乐. 基于SPECT/CT的甲状腺摄锝率的测定[J]. 中国医疗设备, 2017, 32(4): 79-82.
LIU Ren-cong, ZHANG Le-le. Determination of Thyroid Uptaken Technetium Rate Based on the
SPECT/CT. China Medical Devices, 2017, 32(4): 79-82.