1. a. Department of Nuclear Medicine; b. Department of Medical Equipment, Nanjing first Hospital, Nanjing Medical University,
Nanjing Jiangsu 210006, China; 2. Nanjing health information center, Nanjing Jiangsu 210003, China
Abstract：Objective To investigate the impact of acquisition time per bed on image quality and SUV in 18F-FDG PET imaging.
Methods This study consisted of a phantom study and a retrospective analysis of 23 consecutive patients who underwent clinical
18F-FDG PET/CT. The body phantom of the National Electrical Manufacturers Association and International Electro technical
Commission with a 37-mm-diameter sphere was filled with an 18F-FDG solution with a 4:1 radioactivity ratio compared with the
background. The PET data were reconstructed with the baseline ordered subsets expectation maximization algorithm + PSF + TOF
model. PET image quality was evaluated by visual assessment, the signal-to-noise ratio, the contrast, and the coefficient of variance
in the phantom study and SUVmean, SUVsd, CVliver and tumor SUVmax in clinical study. Results In the phantom study, CV decreased
with increasing acquisition time per bed, SNR showed a rising trend, and contrast reflected a relatively steady trend. In clinical
study, the PET image quality was achieved at five minutes per bed, and the tumors remained clearly visible at two minutes per bed.
In addition, the SUVmean, SUVsd and CVliver were differed significantly among 5 acquisition time-based groups (F=497.10, F=14.59,
F=46.80, P<0.0001), whereas the tumor SUVmax for 5 all acquisition time groups had no significant statistical difference not only
in the overall comparison, but also in the different body mass index and injected dose per weight (all P>0.05). Conclusion Different
acquisition time has an influence on 18F-FDG PET image quality and SUV, and extended acquisition time can effectively suppress
noise. Meanwhile, it is feasible to obtain consistently good quality PET image which can meet clinical diagnostic needs in shorter
acquisition time.
徐磊1a，孟庆乐1a，杨瑞1a，钱鑫宇1a，周蕾蕾1b，蒋红兵1b,2. 每床位采集时间对18F-FDG PET图像质量和SUV值的影响[J]. 中国医疗设备, 2018, 33(11): 28-32.
XU Lei1a, MENG Qingle1a, YANG Rui1a, Qian Xinyu1a, ZHOU Leilei1b, JIANG Hongbing1b,2. Effects of Acquisition Time Per Bed on the Quality of 18F-PDG PET Images and SUV Values. China Medical Devices, 2018, 33(11): 28-32.
