Design of a Miniaturized and Low-Cost Immunofluorescence Analyzer
SHEN Zenggui1, DENG Hongyu2, LIN Xuexiang3
1. Department of Equipment, Nanfang Hospital, Southern Medical University, Guangzhou Guangdong 510515, China; 2. Department
of Rehabilitation, The Third Affilliated Hospital of Southern Medical University, Guangzhou Guangdong 510000, China; 3. Institute
of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen
Guangdong 518055, China
Abstract：Objective To design a miniaturized, low-cost immunofluorescence analyzer with automatic discarding function.
Methods The immunofluorescence analyzer was designed with a non-confocal optical path. The light source was located
on both sides of the optical module, and the photodiode was located directly above the test strip. The optical module used
micro switch to detect the insertion of test trip, used push-rod motor to control the movement of the test strip, and realized
the scanning process of the test card with the silicon photodiode. Results The results showed that the precision of the analyzer
had a CV value of less than 5%, the accuracy of the low-value and intermediate-value was not more than 5%, and the gradient fluid
correlation coefficient was more than 0.99 in the linear range. The immunofluorescence analyzer had well fixed optical module,
simple movement mechanism, with the functions of automatic detection of card insert and automatic discarding of waste card.
Conclusion The new design of the instrument is effective, and can be widely applied in the immunofluorescence of food safety
and animal diseases.
沈增贵1，邓红玉2，林学祥3. 一种小型化低成本免疫荧光分析仪的设计[J]. 中国医疗设备, 2019, 34(5): 54-57.
SHEN Zenggui1, DENG Hongyu2, LIN Xuexiang3. Design of a Miniaturized and Low-Cost Immunofluorescence Analyzer. China Medical Devices, 2019, 34(5): 54-57.
