Abstract：Objective To investigate the clinical application value of multislice
spiral Computed
Tomography Angiography (CTA) with low radiation dose and low contrast-medium dose in coronary
imaging. Methods To identify 200 patients with suspected coronary heart disease and after examination
of patients were randomlLy divided into A group A (n=100, contrast-medium dose was agent for
1.2 mL/kg) and, B group B (n=100, contrast-medium dose was agent for 0.8 mL/kg), further two
patients were randomLly divided into four subgroups, which were subgroup A1, A2, B1 and B2
separately., with Subgroup A1 and B1 (control group) underwentused by (A1, B1 with prospectively
Electrocardiography (ECG) triggereding technique while subgroup (A2) and. B2, using conventional
(low-dose group) byunderwent retrospectively ECG gateding technique) four subgroups of coronary
angiography. All patients’ coronary arteries were examined to , computed between different groups of
contrastmedium
agent doseage, image noise, image quality fraction and radiation dose in the different
groups fraction, and which were performed statistical comparative analysis to themlater. Result
In this study, 194 of 200 patients (97%) were successfully performed CTA for coronary imaging.
① Average dose of contrastmedium
for group A group and group B group was 82.65 mL, and 54.3 mL
respectively. The statistical results showed that the average contrastmedium
dose of group B reduced
34.3% approximately than that of compared with group A group, image noise of group B group was higher
slightly than that of group A group, and the overall image quality fraction was of no statistical significance,
which could meet the clinical diagnostic requirements; ② Comparing the coronary artery images of control
group (subgroup A1, B1) and low-dose group (subgroup A2, B2), Effective Dose (ED) value of subgroup A2
group declined more apparently than that of subgroup A1 with a reduction of about 79.7%, and ED values
of subgroup B2 was also decreased more significantly than that of subgroup B1 with a reduction of
about 78.2%, therefore the difference was statistical significantly. However, image quality fraction was
of no significant difference. Conclusion ① A reasonable contractmedium
dose reduction could meet
the clinical diagnosis requirement for CTA on coronary artery; ② A reasonable choice of scanning and scanning parameters could reduce the effective radiation dose without degrading the image quality.
