Application of 18F-FDG PET/CT Combined with MRI for the Evaluation of
Lateral Lymph Node Metastasis in Rectal Cancer
WANG Zheng, XIAO Guoyou, LAI Shaolv, JIN Guanqiao, XIE Dong, LI Liya, TIAN Lianfen, LIANG Binling,
ZHOU Chuanji, WEI Hongjiao, CHAI Hua, YANG Zhi
Department of Medical Imaging, Guangxi Medical University Affiliated Tumor Hospital, Guangxi Clinical Medical Research
Center of Imaging Medicine, Guangxi Key Clinical Specialty (Department of Medical Imaging), Advantage Cultivation Discipline
(Department of Medical Imaging), Nanning Guangxi 530021, China
Abstract：Objective To investigate the application value of 18F-FDG PET/CT combined with MRI to evaluate for the assessment
of lateral lymph node metastasis in rectal cancer. Methods Retrospective analyzed 33 and 45 metastatic and non-metastatic lymph
nodes confirmed by surgical pathology in 51 rectal cancer patients, compared to the short diameter, SUVmax, and ADC values between
the two groups, and explored the diagnostic value of different indexes and combinations indexes. Results There were no statistically
significant differences in the measurement of metastatic and non-metastatic lymph node short diameters of PET/CT and MRI (P>0.05).
MRI short diameter ≥6.75 mm and PET/CT short diameter≥5.05 mm were the diagnostic criteria for metastatic lymph nodes,
the difference in specificity and accuracy is not significant (P>0.05). Combined diagnosis of PET/CT short diameter ≥5.05 mm
combined with T2WI signal unevenness, its sensitivity, specificity and accuracy were significantly improved (P<0.05). The difference
in ADC values and SUVmax values of non-metastatic lymph nodes and metastatic lymph nodes were not statistically significant
(P>0.05). SUVmax ≥1.45 and ADC value≤1.049 were used as the diagnostic criteria for metastatic lymph nodes, respectively,
while the sensitivity, specificity and accuracy of SUVmax≥1.45 combined with ADC value≤1.049×10-3 mm2/s for the diagnosis of
metastatic lymph nodes were significantly improved (P<0.05). Conclusion 18F-FDG PET/CT combined with MRI multi-modality
imaging has high clinical application value in lateral lymph node metastasis of rectal cancer, and provides more accurate N staging
information for pre-treatment staging.
王铮，肖国有，赖少侣，金观桥，谢东，李丽娅，田连芬，梁彬玲，周传集，韦红娇，柴华，杨志. 18F-FDG PET/CT联合MRI评估直肠癌侧方淋巴结转移的应用研究[J]. 中国医疗设备, 2021, 36(7): 89-92.
WANG Zheng, XIAO Guoyou, LAI Shaolv, JIN Guanqiao, XIE Dong, LI Liya, TIAN Lianfen, LIANG Binling,
ZHOU Chuanji, WEI Hongjiao, CHAI Hua, YANG Zhi. Application of 18F-FDG PET/CT Combined with MRI for the Evaluation of
Lateral Lymph Node Metastasis in Rectal Cancer. China Medical Devices, 2021, 36(7): 89-92.
