摘要本文使用全视野数字化乳腺X线成像（Full-Field Digital Mammography，FFDM）、数字化乳腺X线三维断层摄影技术（Digital Breast Tomosynthesis，DBT），以病理诊断结果作为“金标准”，取58例（60个病灶）样本进行回顾性研究。研究发现，DBT诊断肿瘤大小测量值与病理诊断比较，差异无统计学意义（P>0.05）|而FFDM诊断肿瘤大小测量值显著大于病理诊断结果（P<0.05）|DBT在10~20 mm病灶诊断特异性显著高于FFDM诊断（P<0.05）|DBT原位癌、非原位癌诊断准确率分别为90.91%、97.96%，总准确率为95.00%，显著高于FFDM诊断（P<0.05）。因此，相对于FFDM，DBT用于乳腺癌诊断，能更加精确地测量病灶大小，且对于10~20 mm径线范围内肿块的诊断特异性更高。DBT对原位癌的诊断未体现出明显优势，但对非原位癌的诊断准确性更高。
Abstract：With pathological diagnosis results as the “gold standard”, the clinical data of 58 cases (60 lesions) samples was analyzed retrospectively by full-?eld digital mammography (FFDM) and digital breast tomosynthesis (DBT). The study showed that there was no statistically signi?cant difference between the measured value of the tumor size diagnosed by DBT and the pathological diagnosis (P>0.05)| while the measured value of the tumor size diagnosed by FFDM was significantly larger than the result of pathological diagnosis (P<0.05)| the diagnostic speci?city in 10~20 mm lesions by DBT was signi?cantly higher than the diagnosis of FFDM (P<0.05)| the diagnostic accuracy of DBT carcinoma in situ and non-in situ carcinoma were 90.91% and 97.96%, respectively, and the total accuracy rate was 95.00%, which was signi?cantly higher than diagnosis of FFDM (P<0.05). Therefore, compared with FFDM, DBT can more accurately measure the size of the lesion, and has a higher speci?city for the diagnosis of tumors in the diameter range of 10~20 mm for breast cancer diagnosis. DBT does not show obvious advantages in the diagnosis of carcinoma in situ, but it has higher accuracy in the diagnosis of carcinoma in situ.
谭琬琳，孙剑宁，李艳辉. 数字化乳腺X线摄影与三维断层摄影对乳腺癌初诊价值的比较分析[J]. 中国医疗设备, 2020, 35(10): 160-163.
TAN Wanlin, SUN Jianning, LI Yanhui. A Comparative Analysis of Full-field Digital Mammography and Digital Breast Tomosynthesis
in the Diagnosis of Breast Cancer. China Medical Devices, 2020, 35(10): 160-163.
