Abstract：Objective To investigate the stability and repeatability ofintra-voxel incoherent motion diffusion-weighted imaging (IVIM-DWI) model based on different combinations of diffusion-sensitive gradient factor (b) values in retroperitoneal tumors, and to optimize the optimal combination of bvalues of IVIM-DWI model. Methods The imaging and pathological data of 53 patients with retroperitoneal tumor who underwent routine MRI and IVIM-DWI were analyzed retrospectively. Five groups of different combinations of b values were set (I group: 0, 10, 20, 50, 100, 150, 200, 500, 800, 1000 s/mm2|Ⅱgroup: 0, 100, 200, 300, 400, 500, 600, 700, 800, 900 s/mm2|Ⅲ group: 0, 50,100, 200, 400, 600, 800, 1000, 1200, 1400 s/mm2|Ⅳ group: 0, 50, 150, 500, 1000 s/mm2|V group: 0, 20, 100, 200, 800 s/mm2). Among them, 21 cases adopted the combination of bvalues in Ⅰ+Ⅱ+Ⅲ group, and 32 cases adopted the combination of b-values inⅠ+Ⅳ+Ⅴ group. IVIM-DWI quantitative parameters (D value, f value, D* value and ADC value) of each group were measured, and the image quality was evaluated by Likert 5 subscale method. Results There were no signi?cant differences in IVIM-DWI related quantitative parameters (D value, f value, D* value and ADC value) and image quality score (P>0.05) in Ⅰ+Ⅱ+Ⅲ group, while the D value, D* value and ADC value of the Ⅲ group were signi?cantly lower than those of the other four groups (P<0.05), and the image quality score was the lowest. The f value and D* value of group Ⅴ were signi?cantly different from those of Ⅰ, Ⅱ and Ⅳ groups (P<0.05). In addition, the IVIM-DWI sequence scanning time of the combination of b values in Ⅰ, Ⅱ and Ⅲ groups was approximately 2 times as long as that in Ⅳ and Ⅴ groups. Conclusion The stability and repeatability of IVIM-DWI related quantitative parameters of b value combinations in Ⅰ, Ⅱ and Ⅳ groups were optimal, among which the image quality of Ⅰgroup was the best, while the scanning time of sequence of Ⅳ group was the shortest. In clinical work, an appropriate combination of b values canbe selected according to the actual situation of patients.
张屹俊，张九龙，单飞，施楠楠，齐华丽，宋朋睿，章礽荫. 体素内不相干运动扩散加权威像在评价腹膜后肿瘤中的b值
优化方案研究[J]. 中国医疗设备, 2020, 35(10): 142-146.
ZHANG YiJun, ZHANG Jiulong, SHAN Fei, SHI Nannan, QI Huali, SONG Pengrui, ZHANG Rengyin. Study on b Value Optimization Scheme of Intra-Voxel Incoherent Motion Diffusion-Weighted
Imaging in the Evaluation of Retroperitoneal Tumors. China Medical Devices, 2020, 35(10): 142-146.
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